Publications related to Organizational structure

Graph generative deep learning models with an application to circuit topologies

Modern integrated circuits are tiny yet incredibly complex technological artifacts, composed of millions and billions of individual structures working in unison. Managing their complexity and facilitating their design drove part of the co-evolution of mode ...

EPFL2024

Machine Learning Security in Industry: A Quantitative Survey

Kathrin Grosse

Despite the large body of academic work on machine learning security, little is known about the occurrence of attacks on machine learning systems in the wild. In this paper, we report on a quantitative study with 139 industrial practitioners. We analyze at ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2023

Controlling the Microstructure and Composition of 3D Printed Soft Load-Bearing Hydrogels

Matteo Hirsch

Hydrogels are among the first materials expressly designed for their use in biomedicine. However, state-of-the-art applications of hydrogels are severely limited because they are typically either too soft or too brittle such that they cannot bear significa ...

EPFL2023

A conceptual construct on value for infrastructure asset management

Matthias Finger

Understanding the meaning of value to asset-intensive organizations and their stakeholders has been a long -standing goal of researchers and managers of the asset management community. These issues have become particularly prominent with the publication of ...

ELSEVIER SCI LTD2022

Engineering of Existing Structures: The Need and Place for Non-destructive Evaluation

Eugen Brühwiler, Numa Joy Bertola, Thomas Schumacher

Structural engineers today are still educated mainly to design new structures. This ignores the fact that structures already exist and need to be maintained. Students are thus often ill-equipped to deal with maintenance and preservation of existing structu ...

2022

Hierarchical tensile structures with ultralow mechanical dissipation

Tobias Kippenberg, Sergey Fedorov, Alberto Beccari, Amirali Arabmoheghi, Nils Johan Engelsen

Structural hierarchy is found in myriad biological systems and has improved man-made structures ranging from the Eiffel tower to optical cavities. In mechanical resonators whose rigidity is provided by static tension, structural hierarchy can reduce the di ...

Nature Portfolio2022

Population-scale dietary interests during the COVID-19 pandemic

Robert West, Kristina Gligoric

The SARS-CoV-2 virus has altered people's lives around the world. Here we document population-wide shifts in dietary interests in 18 countries in 2020, as revealed through time series of Google search volumes. We find that during the first wave of the COVI ...

Nature Portfolio2022

From vesicles to materials: bioinspired strategies for fabricating hierarchically structured soft matter

Esther Amstad

Certain organisms including species of mollusks, polychaetes, onychophorans and arthropods produce exceptional polymeric materials outside their bodies under ambient conditions using concentrated fluid protein precursors. While much is understood about the ...

ROYAL SOC2021

Designing Horizontality

Paola Viganò, Tommaso Pietropolli

This paper is divided into three parts. The first introduces a trilogy of concepts and figures of the discourse. The concept of isotropy, as opposed to hierarchy, evokes the same conditions in all directions. The concept of porosity tackles the fluidity an ...

ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD2021

Microtensile failure mechanisms in lamellar bone: Influence of fibrillar orientation, specimen size and hydration

Johann Michler, Daniele Casari, Tatiana Kochetkova

A mechanistic understanding of bone fracture is indispensable for developing improved fracture risk assessment in clinics. Since bone is a hierarchically structured material, gaining such knowledge requires analysis at multiple length scales. Here, the ten ...

ELSEVIER SCI LTD2021

Belief Control Strategies for Interactions Over Weakly-Connected Graphs

Ali H. Sayed, Bicheng Ying

In diffusion social learning over weakly-connected graphs, it has been shown recently that influential agents shape the beliefs of non-influential agents. This paper analyzes this mechanism more closely and addresses two main questions. First, the article ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Hierarchical Control of Islanded Microgrids with Flexible Structures

Pulkit Nahata

The primary objective of this doctoral thesis is the design and development of hierarchical control schemes for the overall operation and control of Islanded mGs (ImGs) with flexible structuresâ or, with no reference topologies. The control methodologies ...

EPFL2021

Palimpsest Metaphor: Figures and Spaces of the Contemporary Project

Paola Viganò

What are the consequences of the use of the palimpsest metaphor on the construction of the contemporary project? The metaphor casts criticism on the modern project and opens to the long-term (longue durée). The investigation of territorial rationalities br ...

2020

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

Hilal Lashuel, Graham Knott, Marion Leleu, Fabien Kuttler, Anne-Laure Mahul Mellier, Mary-Claude Croisier-Coeytaux, Johannes Burtscher, Niran Maharjan, Laura Emmeline H Weerens

Parkinson’s disease (PD) is characterized by the accumulation of misfolded and aggregated α-synuclein (α-syn) into intraneuronal inclusions named Lewy bodies (LBs). Although it is widely believed that α-syn plays a central role in the pathogenesis of PD, t ...

National Academy of Sciences2020

Helical structures with switchable and hierarchical chirality

Huijuan Feng

Chirality is present as a trend of research in biological and chemical communities for it has a significant effect on physiological properties and pharmacological effects. Further, manipulating specific morphological chirality recently has emerged as a pro ...

AMER INST PHYSICS2020

Development of chemical biology tools to reveal the function and organization of the silenced chromatin state

Nora Guidotti

Effector proteins are recruited to chromatin via transient interactions between their reader domains and histone post-translational modification (PTM) patterns. These interactions form signaling pathways that control gene expression or repression and which ...

EPFL2020

Testing Analytical Frameworks in Transdisciplinary Research for Sustainable Development

Jean-Claude Bolay, Gabriela Tejada Guerrero, Silvia Hostettler, Clémence Noëlie Marie Ranquet Bouleau, Marina Cracco

This article discusses the concept and the practice of transdisciplinary research, including how it is conceived and implemented through the cooperation of different actors involved. With transdisciplinarity gaining recognition as an approach to addressing ...

2019

X-Shell Pavilion: A Deployable Elastic Rod Structure

Mark Pauly, Florin Isvoranu, Tian Chen, Francis Julian Panetta, Etienne Bouleau

We present the X-Shell pavilion, a lightweight structure composed of elastic beam elements joined in a special layout that allows easy on-site deployment. The structure’s undeployed assembly configuration lies mostly flat and is easy to build, consisting o ...

Ingenta2019

Meeting Report – The 2019 FEBS special meeting on sphingolipid biology: sphingolipids in physiology and pathology

Giovanni D'Angelo

Sphingolipids are a fundamental class of molecules that are involved in structural, organizational and signaling properties of eukaryotic membranes. Defects in their production or disposal lead to acquired and inherited human diseases. A growing community ...

2019

Routines and Practices in Cross-boundary Creative Projects

Giada Baldessarelli

In the past decades, literature on routines and practices has substantially contributed to our understanding of how actors accomplish organizational tasks through repetitive and recognizable patterns of interdependent actions situated in time and space. Ye ...

EPFL2018