Nuclear receptor

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Biology
Cell biology
Receptor (biochemistry)

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Related lectures (27)

Nuclear Receptors: Signalling and Health Implications

Explores nuclear receptors, JAK-STAT pathway, growth factors, endocrine disruptors, and estrogen receptors.

Nuclear Receptors: Structure and Evolution

Explores the structure and evolution of nuclear hormone receptors, from basic steroid hormone structure to key mutations in resurrected proteins.

Nuclear Receptors: Drug Targets

Explores nuclear receptors, their role in drug pharmacology, and physiological functions in adipose tissue and glucose homeostasis.

Nuclear Receptors: Core Signaling

Explores nuclear receptors' core signaling and the impact of endocrine disruptors on the endocrine system, including the inhibitory effects of compounds like eugenol on the estrogen receptor.

Drug Targets: Nuclear Receptors

Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.

Nuclear Receptors: Coactivators and Transcriptional Modulation

Explores coactivators' role in transcriptional modulation, histone acetylation, ERa antagonists, and tissue-specific actions of nuclear receptors.

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Pharmacology: Drug Targets and Mechanisms

Discusses ligand-receptor binding, drug targets, insulin physiology, NSAIDs, and tyrosine kinase inhibitors.

Targeting: Biomaterials and Therapeutics

Delves into passive and active targeting mechanisms in biomaterials for therapeutic delivery to diseased cells, emphasizing the use of liposomes.

Receptor-Ligand Interaction

Explores receptor-ligand interactions, covering binding, dissociation, equilibrium, and quantification methods.

Pharmacodynamics exercises

Covers the analysis of binding measurements and toxin kinetics in pharmacodynamics.

Receptor-Ligand Interaction: Quantification and Mechanisms

Explores methods to quantify receptor-ligand interactions, ligand-gated ion channels, and the Hill equation.

Endocrinology Basics: Hormones and Receptors

Explores the properties and functions of different hormone types in the endocrine system, including polypeptides, modified amino acids, and steroids.

Pharmacodynamics: Ligand-Receptor Binding Kinetics

Explores ligand-receptor binding kinetics, concentration-effect relationship, and drug therapy impact.

Endocytosis of Materials

Delves into the significance of size, shape, and charge in cellular endocytosis processes, emphasizing the design of materials for efficient cellular uptake.

Pharmacodynamics: Ligand-Receptor Interactions and Drug Effects

Explores ligand-receptor interactions, drug effects, modulation mechanisms, and factors influencing drug responses.

Pharmacodynamics: Quantitative Description of Ligand-Receptor Binding

Delves into the quantitative aspects of ligand-receptor binding and receptor occupancy.

Pharmacodynamics: Ligand-Receptor Binding and Drug Effects

Explores ligand-receptor binding, drug effects, efficacy, potency, and biased agonism in pharmacodynamics.

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Protein Folding: Forces and Mechanisms

Explores protein folding forces, including van der Waals interactions, hydrogen bonds, and salt bridges, and their impact on stability.

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