Publications related to Good manufacturing practice

A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions

Dominique Pioletti, Peyman Karami, Theofanis Stampoultzis, Yanheng Guo

The drive to develop cartilage implants for the treatment of major defects in the musculoskeletal sys-tem has resulted in a major research thrust towards developing biomaterial devices for cartilage repair. Investigational devices for the restoration of ar ...

ELSEVIER SCI LTD2023

All-Solid-State Ion-Selective Electrodes: A Tutorial for Correct Practice

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Irene Taurino, Francesca Criscuolo

The research on ion-measuring devices has seen a rapid expansion in the last years as a consequence of the growing interest in wearable sensors for biofluids analysis and in portable devices for remote or in-line water and food quality monitoring. As a res ...

2021

Load Balancing Video Clients in Enterprise Wireless Networks

Dan-Cristian Tomozei, Lorenzo Granai, Aswin Suresh, Sergio Mena

Given the increasing popularity of real-time video communication over enterprise wireless networks, ensuring good quality of experience is becoming critical. A common problem in such networks is that the clients typically adopt the strategy of associating ...

IEEE2018

Building up Resilience in a Pharmaceutical Supply Chain through Inventory, Dual Sourcing and Agility Capacity

Ralf Seifert, Florian Christopher Matthias Lücker

This paper is inspired by a risk management problem faced by a leading pharmaceutical company. Key operational risk mitigation measures include Risk Mitigation Inventory (RMI), Dual Sourcing and Agility Capacity. We study the relationship between these thr ...

2017

Design, simulation, and quality evaluation of micro-optical freeform beam shapers at different illumination conditions

Hans Peter Herzig, Daniel Infante Gómez

A design method to generate thin micro-optical freeform (MOF) beam shapers by clipping or wrapping an original and much thicker freeform surface is provided. MOF elements are situated at the border between refractive and diffractive optical elements. The i ...

Optical Soc Amer2016

Transient Gene Expression in HEK-293E Cells for Recombinant Protein Production : Process Characterization towards GMP Approval

Sophie Nallet

The growing demand of biopharmaceutical products is boosting the market for therapeutic recombinant proteins (r-proteins). More than half of the 140 r-proteins that have gained approval for human therapeutic use are manufactured in mammalian cells that mak ...

EPFL2010

Gallium arsenide p-i-n radial structures for photovoltaic applications

Michael Graetzel, Anna Fontcuberta i Morral, Martin Heiss, Carlo Colombo

Gallium arsenide p-i-n radial junctions were fabricated by molecular beam epitaxy. The current-voltage characteristics of single nanowires were measured in the dark and under various illumination conditions including 1.5 AM. The total efficiency was 4.5%. ...

American Institute of Physics2009

Caractérisation de la génération et la propagation d'ondes de pressions dans des tissus biologiques pour la conception d'appareils médicaux

Mathieu Benoit

Therapies using so called extracorporeal shock waves (Extracorporeal Shock Wave Therapy ESWT) have become current medical practice in orthopedy and traumatology. In order to understand and to optimize the effect of shock waves in clinical applications, med ...

EPFL2009

Fabrication of arrays of sub-wavelength nano-apertures in an optically thick gold layer on glass slides for optical studies

Theo Lasser, Patrik Willi Hoffmann, Benjamin Dwir, Ivo Utke, Marcel Leutenegger, Alexandre Perentes

We report on the fabrication of two-dimensional arrays of nano-optical apertures in gold layers by electron beam lithography (EBL) on a transparent glass substrate. 30 x 30 μ m(2) large arrays of high aspect ratio sub-wavelength cylinders (400 nm diameter ...

2005