Explores the selection and rationale behind preclinical animal models in drug discovery, emphasizing understanding mechanisms of action and domain specificity.
Explores the selection and rationale of preclinical animal models in drug development, emphasizing the 10 to 15-year path to a marketed small-molecule drug.
Delves into retooling the genetic code by expanding it beyond the standard amino acids, with a focus on eukaryotic mRNA translation and site-specific incorporation in fruit fly models.