Publications related to Third-degree atrioventricular block

Evaluation and optimization of novel extraction algorithms for the automatic detection of atrial activations recorded within the pulmonary veins during atrial fibrillation

Jean-Marc Vesin, Adrian Luca, Yann Prudat, Sasan Yazdani, Etienne Pruvot

Background and objective The automated detection of atrial activations (AAs) recorded from intracardiac electrograms (IEGMs) during atrial fibrillation (AF) is challenging considering their various amplitudes, morphologies and cycle length. Activation time ...

BMC2022

Arterial Wave Reflection and Aortic Valve Stenosis: Diagnostic Challenges and Prognostic Significance

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou

IntroductionArterial wave reflection is an important component of the left ventricular afterload, affecting both pressure and flow to the aorta. The aim of the present study was to evaluate the impact of wave reflection on transvalvular pressure gradients ...

FRONTIERS MEDIA SA2022

AI-Based Estimation of End-Systolic Elastance From Arm-Pressure and Systolic Time Intervals

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou

Left ventricular end-systolic elastance (Ees) is a major determinant of cardiac systolic function and ventricular-arterial interaction. Previous methods for the Ees estimation require the use of the echocardiographic ejection fraction (EF). However, given ...

2021

Modular Design and Optimization of Biomedical Applications for Ultra-Low Power Heterogeneous Platforms

David Atienza Alonso, Miguel Peon Quiros, Simone Machetti, Luca Benini, Benoît Walter Denkinger, Elisabetta De Giovanni, Fabio Montagna

In the last years, remote health monitoring is becoming an essential branch of health care with the rapid development of wearable sensors technology. To meet the demand of new more complex applications and ensuring adequate battery lifetime, wearable senso ...

2020

Extensive and diverse patterns of cell death sculpt neural networks in insects

Pavan P Ramdya, Chin-Lin Chen

Changes to the structure and function of neural networks are thought to underlie the evolutionary adaptation of animal behaviours. Among the many developmental phenomena that generate change programmed cell death (PCD) appears to play a key role. We show t ...

2020

REWARD: Design, Optimization, and Evaluation of a Real-Time Relative-Energy Wearable R-Peak Detection Algorithm *

David Atienza Alonso, Jean-Marc Vesin, Sasan Yazdani, Lara Orlandic, Adriana Arza Valdes, Elisabetta De Giovanni

Wearable devices are an unobtrusive, cost-effective means of continuous ambulatory monitoring of chronic cardiovascular diseases. However, on these resource-constrained systems, electrocardiogram (ECG) processing algorithms must consume minimal power and m ...

2019

Computational fluid dynamics of blood flow in an idealized left human heart

Alfio Quarteroni, Filippo Menghini

We construct an idealized computational model of the left human heart for the study of the blood flow dynamics in the left atrium and ventricle. We solve the Navier-Stokes equations in the ALE formulation and we prescribe the left heart wall displacement b ...

Wiley2019

Multi-DoF Force Characterization of Soft Actuators

Jamie Paik, Sagar Dattatray Joshi

Soft actuators provide highly adaptable actuator options for applications in wearable devices, grippers and mobile robots due to their inherent compliance. However, this compliance causes soft actuators to have virtually infinite degrees of freedom (DoF) o ...

2019

The Center of Small Quantum Groups I: The Principal Block in Type A

Anna Lachowska

We develop an elementary algebraic method to compute the center of the principal block of a small quantum group associated with a complex semisimple Lie algebra at a root of unity. The cases of sl(3) and sl(4) are computed explicitly. This allows us to for ...

OXFORD UNIV PRESS2018

3D phase contrast MRI: Partial volume correction for robust blood flow quantification in small intracranial vessels

Mohamed Farhat, Pierre Bouillot

Purpose: Recent advances in 3D-PCMRI (phase contrast MRI) sequences allow for measuring the complex hemodynamics in cerebral arteries. However, the small size of these vessels vs spatial resolution can lead to non-negligible partial volume artifacts, which ...

Wiley2018

Noninvasive Stroke Volume Monitoring by Electrical Impedance Tomography

Fabian Braun

In clinical practice it is of vital importance to track the health of a patient's cardiovascular system via the continuous measurement of hemodynamic parameters. Cardiac output (CO) and the related stroke volume (SV) are two such parameters of central inte ...

EPFL2018

Signal Processing Approaches for Cardio-Respiratory Biosignals with an Emphasis on Mobile Health Applications

Leila Mirmohamadsadeghi

We humans are constantly preoccupied with our health and physiological status. From precise measurements such as the 12-lead electrocardiograms recorded in hospitals, we have moved on to mobile acquisition devices, now as versatile as smart-watches and sma ...

EPFL2017

A Patient-Specific Methodology for Prediction of Paroxysmal Atrial Fibrillation Onset

David Atienza Alonso, Jean-Marc Vesin, Amir Aminifar, Adrian Luca, Sasan Yazdani, Elisabetta De Giovanni

In spite of the progress in management of Atrial Fibrillation (AF), this arrhythmia is one of the major causes of stroke and heart failure. The progression of this pathology from a silent paroxysmal form (PAF) into a sustained AF can be prevented by predic ...

2017

Flutter Suppression of a Bridge Section Model Endowed with Actively Controlled Flap Arrays

Alcherio Martinoli, Klara Maria Boberg, Glauco Feltrin

In this work, we investigate active flutter control of a bridge section model equipped with arrays of flaps. We consider three simple control algorithms based on an amplitudegain and a phase-shift for actuating the flaps and stabilizing the section model. ...

2015

Development of Implantable Electrodes Based on Polymer Derived Ceramics

Jonas Grossenbacher

The invention of heart pacemakers in the 50's aims to help patients to overcome heart strokes, which represent the first cause of death worldwide. In Europe and in the USA, more than 3000 pacemakers are implanted every day. Despite the constant evolution o ...

EPFL2015

Response of an Embedded Block Impacted by High-Velocity Jets

Matteo Paolo Elia Antonio Federspiel

High-velocity plunging jets, issuing from ood release structures of dams, may result in scouring of the rocky riverbed and even endanger the foundation of the dams. Assessment of the scour extent is essential to ensure the safety of the dam and appurtenant ...

EPFL2011

Study of the effect of rapid pacing of atrial fibrillation on the non-paced atrium

Jean-Marc Vesin, Laurent Renaud Uldry, Lukas Kappenberger

Purpose: Experimental studies showed that local capture of atrial fibrillation (AF) by rapid pacing was possible in humans. However, contradictory observations were reported on its effect at distant atrial sites. The present model-based study investigated ...

2011

Biomechanical, morphological and zero-stress state characterization of jugular vein remodeling in arteriovenous fistulas for hemodialysis

Nikolaos Stergiopoulos

While the role of hemodynamic variables on the development of intimal hyperplasia in arteriovenous fistulas for hemodialysis has been examined, less is known about the intramural biomechanical factors. In this study, arteriovenous fistulas were created by ...

2010

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

Freddy Radtke, Ute Koch, Alexandre José Pessanha De Oliveira Caimoto Duarte

Thymic T cell lineage commitment is dependent on Notch1 (N1) receptor-mediated signaling. Although the physiological ligands that interact with N1 expressed on thymic precursors are currently unknown, in vitro culture systems point to Delta-like 1 (DL1) an ...

2008