Coefficient of relationship

The coefficient of relationship is a measure of the degree of consanguinity (or biological relationship) between two individuals. The term coefficient of relationship was defined by Sewall Wright in 1922, and was derived from his definition of the coefficient of inbreeding of 1921. The measure is most commonly used in genetics and genealogy. A coefficient of inbreeding can be calculated for an individual, and is typically one-half the coefficient of relationship between the parents. In general, the higher the level of inbreeding the closer the coefficient of relationship between the parents approaches a value of 1, expressed as a percentage, and approaches a value of 0 for individuals with arbitrarily remote common ancestors. The coefficient of relationship () between two individuals B and C is obtained by a summation of coefficients calculated for every line by which they are connected to their common ancestors. Each such line connects the two individuals via a common ancestor, passing through no individual which is not a common ancestor more than once. A path coefficient between an ancestor A and an offspring O separated by generations is given as: where and are the coefficients of inbreeding for A and O, respectively. The coefficient of relationship is now obtained by summing over all path coefficients: By assuming that the pedigree can be traced back to a sufficiently remote population of perfectly random-bred stock (fA = 0 for all A in the sum) the definition of r may be simplified to where p enumerates all paths connecting B and C with unique common ancestors (i.e. all paths terminate at a common ancestor and may not pass through a common ancestor to a common ancestor's ancestor), and L(p) is the length of the path p. To give an (artificial) example: Assuming that two individuals share the same 32 ancestors of n = 5 generations ago, but do not have any common ancestors at four or fewer generations ago, their coefficient of relationship would be which for n = 5, is, , or approximately 0.0313 or 3%.