Stewart Cole, Florence Pojer, Claudia Sala, Ruben Hartkoorn, Sophie Magnet, Jeffrey Chen
The tolerance of Mycobacterium tuberculosis to anti-tuberculosis drugs is a major reason for the lengthy therapy needed to treat a tuberculosis infection. Rifampin is a potent inhibitor of RNA polymerase (RNAP) in vivo, but has been shown to be less effect ...
American Society for Microbiology2010