Publications related to Angioplasty

HTATIP2 regulates arteriogenic activity in monocytes from patients with limb ischemia

Michele De Palma, Mario Leonardo Squadrito

Use of autologous cells isolated from elderly patients with multiple comorbidities may account for the modest efficacy of cell therapy in patients with chronic limb threatening ischemia (CLTI). We aimed to determine whether proarteriogenic monocyte/macroph ...

Amer Soc Clinical Investigation Inc2023

Modified pressure-cooker technique (PCT) using extra-soft Kaneka coils improves embolization of high-grade cerebral arteriovenous malformations: a technical note

Mahmut Yüksel

Endovascular embolization techniques are showing an extraordinary potential to treat patients suffering from complex neurovascular malformations. The embolization with liquid embolic agents via Onyx is a prominent approach to treat arteriovenous malformati ...

SPRINGERNATURE2023

Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study

Jacques Fellay, Christian Axel Wandall Thorball

Leukocyte count is associated with coronary artery disease (CAD) events in the general population. Here we show that leukocytes are independently associated with CAD events in people with HIV in Switzerland, after adjusting for traditional and HIVrelated r ...

OXFORD UNIV PRESS INC2023

Sensor-integrated ultraflexible endovascular devices

Lucio Feo Pancaldi-Giubbini

Medical interventions in the central nervous system (CNS) are challenging due to the complexity and delicacy of the brain tissue. Techniques that do not require opening the skull would alleviate patient discomfort and increase post-operative outputs. Vesse ...

EPFL2022

Coronary Artery Disease-Associated and Longevity-Associated Polygenic Risk Scores for Prediction of Coronary Artery Disease Events in Persons Living With Human Immunodeficiency Virus: The Swiss HIV Cohort Study

Jacques Fellay, Christian Axel Wandall Thorball

Background: Coronary artery disease (CAD) is in part genetically determined. Aging is accentuated in people with human immunodeficiency virus (HIV) (PLWH). It is unknown whether genetic CAD event prediction in PLWH is improved by applying individual polyge ...

OXFORD UNIV PRESS INC2021

Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice

Johan Auwerx, Hongwei Zhu, Yuan Liu, Yan Liu, Shuai Shao

Background NCOR1 (nuclear receptor corepressor 1) is an essential coregulator of gene transcription. It has been shown that NCOR1 in macrophages plays important roles in metabolic regulation. However, the function of macrophage NCOR1 in response to myocard ...

2020

Update on yesterday's dose-Use of delivery log-files for daily adaptive proton therapy (DAPT)

Marco Matter

In daily adaptive proton therapy (DAPT), the treatment plan is re-optimized on a daily basis. It is a straightforward idea to incorporate information from the previous deliveries during the optimization to refine this daily proton delivery. A feedback sign ...

2020

Computational study of the risk of restenosis in coronary bypasses

Alfio Quarteroni, Christian Vergara

Coronary artery disease, caused by the buildup of atherosclerotic plaques in the coronary vessel wall, is one of the leading causes of death in the world. For high-risk patients, coronary artery bypass graft is the preferred treatment. Despite overall exce ...

Springer Heidelberg2017

A computational fluid-structure interaction analysis of coronary Y-grafts

Alfio Quarteroni, Christian Vergara

Coronary artery disease is one of the leading causes of death worldwide. The stenotic coronary vessels are generally treated with coronary artery bypass grafts (CABGs), which can be either arterial (internal mammary artery, radial artery) or venous (saphen ...

Elsevier Sci Ltd2017

Fast simulations of patient-specific haemodynamics of coronary artery bypass grafts based on a POD-Galerkin method and a vascular shape parametrization

Alfio Quarteroni, Gianluigi Rozza, Andrea Manzoni, Elena Faggiano

In this work a reduced-order computational framework for the study of haemodynamics in three-dimensional patient-specific configurations of coronary artery bypass grafts dealing with a wide range of scenarios is proposed. We combine several efficient algor ...

Elsevier2016

Intra-Arterial Drug and Light Delivery for Photodynamic Therapy Using Visudyne (R): Implication for Atherosclerotic Plaque Treatment

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Manish Jain

Photodynamic therapy (PDT), which is based on the activation of photosensitizers with light, can be used to reduce plaque burden. We hypothesized that intra-arterial photosensitizer administration and photo-activation will lead to high and rapid accumulati ...

2016

Self-Navigation with Compressed Sensing for 2D translational Motion Correction in Free-Breathing Coronary MRI: a Feasibility Study

Yves Wiaux, Gilles Puy, Ruud van Heeswijk, Davide Piccini, Gabriele Vincenzo Bonanno

Purpose Respiratory motion correction remains a challenge in coronary magnetic resonance imaging (MRI) and current techniques, such as navigator gating, suffer from sub-optimal scan efficiency and ease-of-use. To overcome these limitations, an image-based ...

Public Library of Science2014

Fast virtual deployment of self-expandable stents: Method and in vitro evaluation for intracranial aneurysmal stenting

Luca Augsburger, Daniel Ruefenacht

Introduction: Minimally invasive treatment approaches, like the implantation of percutaneous stents, are becoming more popular every day for the treatment of intracranial aneurysms. The outcome of such treatments is related to factors like vessel and aneur ...

2012

Nanostructured ceramic coating for deformable medical implants such as stents

Arnaud Tourvieille de Labrouhe

Coronary artery disease is one of the main causes of death in western countries. The standard of care has become the implantation of a coronary stent, i.e. a small metal-mesh tube reopening the lumen of the artery and maintaining the blood flow to the hear ...

EPFL2009

VR simulation of interventional radiology and microsurgery

Fei Wang

Currently trainees typically learn surgery techniques directly on mocks, animals or cadavers. For safety, cost and ethics reasons, one cannot try all possible strategies to achieve efficient learning. Virtual Reality (VR) based surgery training systems int ...

EPFL2009

Nanostructured Ceramic Coatings for Drug Delivery

Heinrich Hofmann, Laurent-Dominique Piveteau, Arnaud Tourvieille de Labrouhe, Karin Dittmar

Drug eluting stents (DES) have been successfully implemented in clinical practice in the treatment against coronary artery disease. Compared to the implantation of bare metal stents, restenosis rates decreased significantly after stenting of DES into coron ...

Materials Research Society, 506 Keystone Drive, Warrendale, Pa 15086-7573 Usa2009

A Real-Time Simulator for Interventional Radiology

Hannes Bleuler, Lindo Robert Duratti, Evren Samur, Fei Wang

Interventional radiologists manipulate guidewires and catheters and steer stents through the patient’s vascular system under X-ray imaging for treatment of vascular diseases. The complexity of these procedures makes trainingmandatory in order to master han ...

2008

Modélisation mécanique de fils pour la simulation chirurgicale

Lindo Robert Duratti

Minimally Invasive Surgery (MIS) represents one of the major progresses in surgery in the last decade. In general, it is based on the application of small body-cuts through which instruments are inserted into the patient's body allowing the surgeon to carr ...

EPFL2008

Treatment of renal artery aneurysm with the multilayer stent

Luca Augsburger, Daniel Ruefenacht, Bastien Chopard, Isabelle Henry

Purpose: To describe a new type of stent consisting of a 3-dimensional (3D) braided tube made of 2 interconnected layers without any covering to treat a renal artery aneurysm. ...

2008

Haptic instrumentation for an interventional radiology simulator

Dejan Ilic

Low trauma, reduced costs and fast recovery are only a few factors why minimally invasive surgery (MIS) is taking over classical surgical methods. Interventional Radiology (IR) is a minimally invasive procedure where thin tubular instruments are steered th ...

EPFL2005