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Related publications (30)

Bistable Puncturing Tool for Retinal Vein Cannulation

Yves Bellouard, Simon Nessim Henein, Charles Baur, Lisa Anaïs Jeanne Bonnefoy

An innovative surgical tool prototype dedicated to safe puncturing has been developed for the treatment of retinal vein occlusions (RVOs). The tool is manufactured monolithically by femtolaser printing in fused silica. It consists of a programmable bistabl ...

2020

Elastic properties of self-organized nanogratings produced by femtosecond laser exposure of fused silica

Yves Bellouard, Pieter Vlugter

Under certain exposure conditions, a femtosecond laser beam focused in the bulk of fused silica leads to the formation of self-organized structures consisting of a series of “nanolayers,” parallel to one another. Remarkably, this laser-induced nanoscale an ...

2020

Ultrafast carbothermal reduction of silica to silicon using a CO2 laser beam

Jaeki Jeong

We report the extraction of silicon via a carbothermal reduction process using a CO2 laser beam as a heat source. The surface of a mixture of silica and carbon black powder became brown after laser beam irradiation for a few tens of seconds, and clear peak ...

NATURE RESEARCH2020

Wavefront shaping and deep learning in fiber endoscopy

Eirini Kakkava

Fiber endoscopy plays an important role in the clinical diagnosis and treatment processes involved in modern medicine. Thin fiber probes can relay information from confined places in the human body that are inaccessible for conventional bulky microscopes. ...

EPFL2020

Photocontrolled release of the anticancer drug chlorambucil with caged harmonic nanoparticles

Sandrine Gerber, Jean-Pierre Wolf, Jérémy Vuilleumier, Raphaël Jovita De Matos, Luigi Bonacina

While chemotherapy is one of the most used treatments in oncology, the systemic administration of chemotherapeutics generally results in undesired damages to healthy tissues and cells, side effects such as severe nausea and leukopenia, and reduced efficacy ...

Wiley-VHCA AG2020

Flexure Pivot Oscillator With Intrinsically Tuned Isochronism

Simon Nessim Henein, Ilan Vardi, Etienne Frédéric Gabriel Thalmann, Mohammad Hussein Kahrobaiyan

The most important property for accurate mechanical time bases is isochronism: the independence of period from oscillation amplitude. This paper develops a new concept in isochronism adjustment for flexure-based watch oscillators. Flexure pivot oscillators ...

2020

Selective femtosecond laser ablation via two-photon fluorescence imaging through a multimode fiber

Demetri Psaltis, Christophe Moser, Damien Claude-Marie Loterie, Eirini Kakkava, Donald Benjaman Conkey, Marilisa Romito

We demonstrate the ability of a multimode fiber probe to provide two-photon fluorescence (TPF) imaging feedback that guides the femtosecond laser ablation (FLA) in biological samples for highly selective modifications. We implement the system through the p ...

OPTICAL SOC AMER2019

Two-photon imaging and selective laser ablation of Cochlea hair cells through a multimode fiber probe

Demetri Psaltis, Christophe Moser, Damien Claude-Marie Loterie, Eirini Kakkava, Marilisa Romito

We demonstrate multimode fiber probe that accomodates dual modality properties for high power ultrashort pulse delivery. A commercially available multimode graded-index (GRIN) fiber is used for two-photon imaging and/or femtosecond laser ablation of Cochle ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Imaging hair cells through laser-ablated cochlear bone

Demetri Psaltis, Ye Pu, Marilisa Romito

We report an innovative technique for the visualization of cells through an overlying scattering medium by combining femtosecond laser bone ablation and two-photon excitation fluorescence (TPEF) microscopy. We demonstrate the technique by imaging hair cell ...

2019

A Numerical Model For The Simulation Of Shallow Laser Surface Melting

Marco Picasso, Alexandre Caboussat, Alexandre Masserey, Julien Hess

We present a multi-physics model for the approximation of the coupled system formed by the temperature-dependent Navier-Stokes equations with free surfaces. The main application is the industrial process of shallow laser surface melting (SLSM), for laser p ...

INT CENTER NUMERICAL METHODS ENGINEERING2019

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