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Related publications (32)

Multifocal stimulation of the cerebro-cerebellar loop during the acquisition of a novel motor skill

Friedhelm Christoph Hummel, Takuya Morishita, Elena Beanato, Maximilian Jonas Wessel, Chang-Hyun Park, Philipp Johannes Koch

Transcranial direct current stimulation (tDCS)-based interventions for augmenting motor learning are gaining interest in systems neuroscience and clinical research. Current approaches focus largely on monofocal motorcortical stimulation. Innovative stimula ...

Nature Research2021

A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

Maria del Carmen Sandi Perez, Cristina Ramona Cudalbu, Jocelin Grosse, Dunja Simicic

Creatine is an organic compound used as fast phosphate energy buffer to recycle ATP, important in tissues with high energy demand such as muscle or brain. Creatine is taken from the diet or endogenously synthetized by the enzymes AGAT and GAMT, and specifi ...

Nature Research2021

Arm-wrist haptic sleeve for drone teleoperation

Dario Floreano, Vivek Ramachandran, Matteo Macchini

Teleoperators rely on both visual and haptic feedback to perform drone teleoperation tasks, such as obstacle avoidance. Haptic feedback becomes essential when visual feedback is compromised, either due to visual occlusions or poor depth perception. However ...

2022

Designing Gamified Activities with Haptic-Enabled Tangible Robots for Therapy and Assistance

Arzu Güneysu Özgür

In this thesis, we contribute to the field of rehabilitation robotics by designing haptic-enabled tangible robot-based activities and exploring their added value for therapy and assistance. The research specifically focuses on the design and development of ...

EPFL2021

Structural control energy of resting-state functional brain states reveals less cost-effective brain dynamics in psychosis vulnerability

Dimitri Nestor Alice Van De Ville, Marie Schaer

How the brain's white-matter anatomy constrains brain activity is an open question that might give insights into the mechanisms that underlie mental disorders such as schizophrenia. Chromosome 22q11.2 deletion syndrome (22q11DS) is a neurodevelopmental dis ...

Wiley2021

Reward boosts reinforcement-based motor learning

Friedhelm Christoph Hummel, Pierre Theopistos Vassiliadis, Julie Duqué

Besides relying heavily on sensory and reinforcement feedback, motor skill learning may also depend on the level of motivation experienced during training. Yet, how motivation by reward modulates motor learning remains unclear. In 90 healthy subjects, we i ...

2021

Clinical value of assessing motor performance in postacute stroke patients

Kamiar Aminian, Anisoara Ionescu, Fabien Massé

Background Rehabilitative treatment plans after stroke are based on clinical examinations of functional capacity and patient-reported outcomes. Objective information about daily life performance is usually not available, but it may improve therapy personal ...

BioMed Central2021

Electrical spinal cord stimulation protocols to regulate neurological functions after spinal cord injury

Salif Axel Komi

Spinal cord injury (SCI) is a life-changing event. People who suffer from it lose their ability to move normally and are subject to life-threatening symptoms. When the insult is not too severe, partial recovery is possible. Otherwise, for severely affected ...

EPFL2021

Development of a peripheral neuroprosthesis to elicit fine hand movements in primates

Marion Aimée Geneviève Badi-Dubois

Neurological disorders such as spinal cord lesion and stroke disturb sensorimotor pathways and result in severe motor deficits that can dreadfully impact the quality of life of affected individuals. Strategies aiming at restoring hand function after upper- ...

EPFL2021

Ultrahigh field in vivo characterization of microstructural abnormalities in the orbitofrontal cortex and amygdala in autism

Elda Fischi Gomez, Cristina Granziera, Nouchine Hadjikhani, Guillaume Bonnier

There are currently no biomarkers for autism spectrum disorder (ASD). This neurodevelopmental condition has previously been associated with histopathological findings, including increased neuronal packing density in the amygdala, abnormal laminar cytoarchi ...

2021

Extending the Spectrum of Dysgraphia: A Data Driven Strategy to Estimate Handwriting Quality

Pierre Dillenbourg, Thibault Lucien Christian Asselborn, Mateo Chapatte

This paper proposes new ways to assess handwriting, a critical skill in any child’s school journey. Traditionally, a pen and paper test called the BHK test (Concise Evaluation Scale for Children’s Handwriting) is used to assess children’s handwriting in Fr ...

Nature Research2020

An inverse optimization approach to understand human acquisition of kinematic coordination in bimanual fine manipulation tasks

Aude Billard, Kunpeng Yao

Tasks that require the cooperation of both hands and arms are common in human everyday life. Coordination helps to synchronize in space and temporally motion of the upper limbs. In fine bimanual tasks, coordination enables also to achieve higher degrees of ...

2020

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