Lectures related to Medicinal chemistry

Interrogating SAR: Medicinal Chemistry

Covers medicinal chemistry basics, high-throughput screening, lead discovery milestones, and compound selectivity in drug optimization.

Interrogating SAR in Medical Chemistry

Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.

Identifying Correct Target in Medical Chemistry

Explores target identification, efficacy, and safety in medical chemistry, emphasizing the importance of on-target specificity and drug design.

Machine Learning for Organic Synthesis

Explores leveraging machine learning for organic synthesis, focusing on predicting reaction yields and dataset predictability.

Atomic Orbitals and Bonding

Explores atomic orbitals' principles and bonding concepts in chemistry.

Using Chemistry to Observe and Manipulate Cells

Explores using chemistry to observe and manipulate cells through the development of fluorescent compounds and stress-inducing reagents.

Identifying Drug Targets: Safety and Efficacy

Delves into identifying drug targets, ensuring efficacy, and maintaining safety in medical chemistry, covering genetic tests, chirality, stereochemistry, drug resistance, and drug-likeness rules.

Generative Models: Advancements in Molecular Design

Explores the use of generative models for discovering novel molecules in molecular design.

The Final Word

Reflects on the journey taken throughout the year and encourages students to persevere.

The Chemistry of Poisonous Frogs: Alkynes and Aromatic Compounds

Explores the chemistry of poisonous frogs and alkynes, highlighting their unique synthesis abilities and medicinal applications.

Heterocyclic Chemistry: Synthesis and Applications

Covers the structure, guidelines, goals, content, and applications of heterocyclic chemistry.

Pharmacokinetic & Pharmacodynamic Studies

Discusses the importance of assessing PK/PD relationships in drug development and the use of multiple PD biomarkers.

Asymmetric Catalysis: Diels-Alder Reactions and Applications

Covers asymmetric catalysis in Diels-Alder reactions, focusing on chiral oxazaborolidinium ions and their applications in fine chemical synthesis.

Organic Chemistry: Aroma Compounds in Flowers

Covers the significance of aroma compounds in flowers and their role in organic chemistry.

Retrosynthesis: Basic Principles and Aromatic Compounds

Covers the basic principles of retrosynthesis and aromatic compounds in organic synthesis.

Platinum Drugs: Chemistry and Cancer Treatment

Covers the role of platinum-based drugs in cancer treatment and their chemical mechanisms.

Organic Chemistry: The Role of Vitamins and Reactions

Discusses the significance of vitamins and radical reactions in organic chemistry.

Protein Reactivity and Chemical Probes

Explores protein reactivity, chemical probes, and quantitative chemoproteomics in biological systems.

Pharmacokinetic & Pharmacodynamic Evaluations

Covers the principles of pharmacokinetics and pharmacodynamics, including drug exposure-response relationships.

Chemical Biology Toolsets: Enzyme Inhibition and Metabolic Signaling

Explores enzyme inhibition, metabolic signaling, glycolysis, and isotopic tracing in central carbon metabolism.