Publications related to Human nutrition

Computational Approaches for Studying Dietary Behaviors with Digital Traces

Human nutrition and dietary habits shape our health, daily life, societies, the environment, and life on earth in general. However, it remains challenging to understand and attempt to change dietary behaviors using traditional methods due to measurement an ...

EPFL2022

Drivers and Barriers Toward Healthy and Environmentally Sustainable Eating in Switzerland: Linking Impacts to Intentions and Practices

Claudia Rebeca Binder Signer, Ivo Philippe Baur, Ralph Hansmann

Food consumption is among the activities with the most significant environmental impacts, and furthermore contributes to rising health costs. We explored the factors that foster or hinder healthy and sustainable eating in Switzerland. Based on an online ho ...

2022

Amoebocytes facilitate efficient carbon and nitrogen assimilation in the Cassiopea -Symbiodiniaceae symbiosis

Anders Meibom, Stéphane Laurent Escrig, Nils Rädecker, Louise Helene Soegaard Jensen, Niclas Heidelberg Lyndby, Sandrine Denise Françoise Bessette, Michael Kühl

The upside-down jellyfish Cassiopea engages in symbiosis with photosynthetic microalgae that facilitate uptake and recycling of inorganic nutrients. By con- trast to most other symbiotic cnidarians, algal endosymbionts in Cassiopea are not restricted to th ...

2020

Towards Win-Win Policies for Healthy and Sustainable Diets in Switzerland

Arnaud Dauriat, Suren Erkman

The first Swiss national dietary survey (MenuCH) was used to screen disease burdens and greenhouse gas emissions (GHG) of Swiss diets (vegan, vegetarian, gluten-free, slimming), with a focus on gender and education level. The Health Nutritional Index (HENI ...

MDPI2020

Intracellular competition for nitrogen controls dinoflagellate population density in corals

Anders Meibom, Stéphane Laurent Escrig, Thomas Krüger, Maoz Fine, Julia Marie Jeanne Yvonne Bodin, Maria-Evangelia Giovani

The density of dinoflagellate microalgae in the tissue of symbiotic corals is an important determinant for health and productivity of the coral animal. Yet, the specific mechanism for their regulation and the consequence for coral nutrition are insufficien ...

ROYAL SOC2020

Food Talks: visual and interaction principles for representing environmental and nutritional food information in augmented reality

Delphine Ribes Lemay, Nicolas Henchoz, Emily Clare Groves, Andreas Sonderegger

This user-centered design research project aimed to investigate visual and interaction principles for augmented reality (AR) in the context of environmental and nutritional food labelling. Nutritional information on existing food labels is often misunderst ...

2019

Global spatial analysis of toxic emissions to freshwater: operationalization for LCA

Anna Kounina Massé

PurposeThere is increasing interest in using fate and exposure models to spatially differentiate the impacts of chemical emissions. This work aims at exploring the operationalization in life cycle assessment (LCA) of spatially differentiated models for tox ...

SPRINGER HEIDELBERG2019

Translating Science Into Business Innovation: The Case of Open Food and Nutrition Data Hackathons

Christopher Tucci, Heidi Christina Gautschi, Gianluigi Viscusi

In this article, we explore the use of hackathons and open data in corporations’ open innovation portfolios, addressing a new way for companies to tap into the creativity and innovation of early-stage startup culture, in this case applied to the food and n ...

2018

More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis

Shi-Yan Caroline Foo

Tuberculosis (TB), whose etiological agent is Mycobacterium tuberculosis (M. tuberculosis), has plagued humanity since antiquity. Even with chemotherapy available today, TB is the leading cause of death due to an infectious disease. Modern day factors, suc ...

EPFL2018

beta-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue

Kristina Schoonjans

beta-Klotho (encoded by Klb) is the obligate coreceptor mediating FGF21 and FGF15/19 signaling. Klb(-/-)mice are refractory to beneficial action of pharmacological FGF21 treatment including stimulation of glucose utilization and thermogenesis. Here, we inv ...

Amer Soc Clinical Investigation Inc2017

Redefining the metabolic landscape through TGF-beta/Activin signaling in Drosophila melanogaster

Wen Bin Chng

Multicellular organisms assess their nutritional state and adapt their metabolic landscape to match their energy demands. In this thesis, we address a longstanding conundrum of how an organism coordinates digestive enzyme expression in response to its nutr ...

EPFL2015

Vitamin E and Vitamin E Acetate Absorption from Self-assembly Systems under Pancreas Insufficiency Conditions

Martin Kussmann

We determined the bioavailability of vitamin E from self-assembly structures in patients with diagnosed chronic pancreas insufficiency. Vitamin E solubilized in dispersed inverted bicontinuous cubic phase and in micellar formulation was delivered directly ...

Swiss Chemical Soc2014

Lactoferrin during lactation protects the immature hypoxic-ischemic rat brain

Yohan Van de Looij

Objective Lactoferrin (Lf) is an iron-binding glycoprotein secreted in maternal milk presenting anti-inflammatory and antioxidant properties. It shows efficient absorption into the brain from nutritional source. Brain injury frequently resulting from cereb ...

2014

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Rolf Gruetter, Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara, Yuhei Takado

Resting skeletal muscle has a preference for the oxidation of lipids compared to carbohydrates and a shift towards carbohydrate oxidation is observed with increasing exercise. Lactate is not only an end product in skeletal muscle but also an important meta ...

2014

From food to physiology characterization and in vitro digestion of milk products and investigation of postprandial metabolism and inflammation after a high-fat meal intake in a human nutrition intervention study

Flurina Schwander

According to the World Health Organization worldwide obesity has more than doubled since 1980. The World health statistics 2012 report shows that one in six adults is obese, one in ten diabetic and one in three has a raised blood pressure. Overweight and o ...

EPFL2013

Microfluidic Ultrafiltration and Acoustophoresis as a Human Breast Milk Optimizing Plateform for Neonatal Nutrition

Blaise Guélat

In recent years, research has highlighted that breast milk with higher concentrations of lipid and protein could benefit to the survival rate and quality of life of preterm infants. However, to date, there is no clinical means available to separate, concen ...

EPFL2013

Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions

Martin Kussmann, Krisztina Nagy

BACKGROUND/OBJECTIVES: The vitamin E derivative, alpha-tocopheryl acetate, is often included in formulations used in enteral nutrition. In this respect, we compared alpha-tocopherol and alpha-tocopheryl acetate absorption under 'maldigestion' conditions, s ...

Nature Publishing Group2013

The NutriChip project - translating technology into nutritional knowledge

Martinus Gijs, Sandro Carrara, Paolo Silacci, Guy Vergères, Flurina Schwander, Reto Portmann

Advances in food transformation have dramatically increased the diversity of products on the market and, consequently, exposed consumers to a complex spectrum of bioactive nutrients whose potential risks and benefits have mostly not been confidently demons ...

Cambridge University Press2012

Gut-associated microbes of Drosophila melanogaster

Bruno Lemaitre, Nichole Broderick

There is growing interest in using Drosophila melanogaster to elucidate mechanisms that underlie the complex relationships between a host and its microbiota. In addition to the many genetic resources and tools Drosophila provides, its associated microbiota ...

2012

Interstitial solute transport in articular cartilage and the role of dynamic compression

Articular cartilage plays important roles in weight-bearing, lubrication, and load distribution in articulating joints. The tissue is mostly extracellular matrix (>90% by volume) that is synthesized and remodeled by cells (chondrocytes) embedded within. Ad ...

EPFL2006