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Related publications (28)

Solar disinfection (SODIS) of viruses in PET bottles

Tamar Kohn, Anna Carratala Ripolles, Michael Jon Mattle, Alex Dionisio Calado

Solar disinfection of drinking water in PET bottles (SODIS) is a simple point-of-use technique efficient for the inactivation of many bacterial pathogens. In contrast, the efficiency of SODIS toward viruses is not well known. In this work, we studied the i ...

American Society for Microbiology2016

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

Francesco Stellacci, Paulo Henrique Jacob Silva, Valeria Cagno, Randy Patrick Carney

Up to 80% of the cost of vaccination programmes is due to the cold chain problem (that is, keeping vaccines cold). Inexpensive, biocompatible additives to slow down the degradation of virus particles would address the problem. Here we propose and character ...

Nature Publishing Group2016

Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses

Jacques Fellay, Istvan Bartha, Christian Hammer, Paul Jack Mc Laren

The magnitude of the human antibody response to viral antigens is highly variable. To explore the human genetic contribution to this variability, we performed genome-wide association studies of the immunoglobulin G response to 14 pathogenic viruses in 2,36 ...

Cell Press2015

Structure of viral membrane-penetrating machines by electron cryo-microscopy and tomography

Sergey Nazarov

My PhD thesis aims to obtain the structure of several bacteriophages, including so-called “jumbo” phages, using the electron cryo-microscopy (cryo-EM) and to study the structural transformation of these viruses as they attach and infect the host cell. We a ...

EPFL2015

UVC inactivation of dsDNA and ssRNA viruses in water: UV fluences and a qPCR-based approach to evaluate decay on viral infectivity

Tamar Kohn, Anna Carratala Ripolles

Disinfection by low-pressure monochromatic ultraviolet (UVC) radiation (253.7 nm) became an important technique to sanitize drinking water and also wastewater in tertiary treatments. In order to prevent the transmission of waterborne viral diseases, the an ...

Springer2014

Virus transfer proportions between gloved fingertips, soft berries, and lettuce, and associated health risks

Anna Carratala Ripolles

Multiple outbreaks of human norovirus (hNoV) have been associated with fresh produce, such as soft berries and lettuce. Even though food handlers are considered an important source for the introduction of hNoV into food chains, their contribution to public ...

Elsevier Science Bv2013

Virus inactivation mechanisms: impact of disinfectants on virus function and structural integrity

Tamar Kohn, Krista Rule Wigginton, Brian Pecson, Anne Thérèse Sigstam, Franziska Sara Bosshard

Oxidative processes are often harnessed as tools for pathogen disinfection. Although the pathways responsible for bacterial inactivation with various biocides are fairly well understood, virus inactivation mechanisms are often contradictory or equivocal. I ...

Amer Chemical Soc2012

Role of Temperature and Suwannee River Natural Organic Matter on Inactivation Kinetics of Rotavirus and Bacteriophage MS2 by Solar Irradiation

Tamar Kohn

Although the sunlight mediated inactivation of viruses has been recognized as an important process that controls surface water quality, the mechanisms of virus inactivation by sunlight are not yet clearly understood. We investigated the synergistic role of ...

2011

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