BIO-373: Genetics and genomics

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Lectures in this course (41)

Genomics: Introduction and Regulatory Networks

Introduces genomics, covers sequencing technologies, genome variation, and explores human genetic linkage maps and RFLP methods.

Genomics: Common vs Rare Diseases

Explores the common vs rare disease variants, GWAS, odds ratios, P-values, and the 'missing heritability' in genetic studies.

Genomics: Structural Variants and Disease Gene Discovery

Explores structural variants in genomics, rare disease detection, and exome sequencing for disease gene discovery.

Genomics: Human Genetic Variation

Explores human genetic variation, blood types, SNP detection, and genome analysis.

Genomics: SNP Detection & Population Stratification

Explores SNP detection, LD bins, and genomics in human history.

Blood Types and Genetic Mutations

Explores blood type inheritance and intriguing human genetic mutations.

Genomics: Chromatin Structure and Organization

Explores chromatin structure, DNA compaction, and regulatory networks in genomics.

Genomics: Transcription Factors and Reprogramming

Explores transcription factors in reprogramming somatic cells to induced pluripotent stem cells and the correlation between Hox gene expression and morphological boundaries.

Genomics: Chromatin Structure and Regulatory Elements

Covers chromatin structure, histone assembly, and regulatory elements in gene expression.

Genomics: Gene Regulatory Networks

Explores gene regulatory networks, protein-DNA interactions, and regulatory elements in genomics.

Genomics: TF Network and ncRNA

Explores SMILE-seq for motif discovery, TF DNA binding affinity, ncRNA genes, and microRNAs.

Gene Regulatory Networks

Delves into gene regulatory networks, ChIP-seq techniques, ENCODE project data interpretation, and differential gene expression modeling.

Genomics: Molecular Basis of Phenotypic Diversity

Delves into the molecular basis of phenotypic diversity, highlighting the role of epigenetics and non-conserved genes in shaping diversity.

Regulatory Variation & Precision Medicine

Explores regulatory variation's impact on precision medicine, focusing on non-coding GWAS SNPs and gene expression variation.

Personalized Medicine: Genetic Make-up Elucidation

Explores the significance of genetic make-up elucidation for personalized medicine, focusing on DNA-based risk assessment and tailored treatments.

Personalized Medicine: Gene Therapy and CRISPR

Explores personalized medicine, gene therapy, CRISPR technology, gene editing strategies, and ethical implications of synthetic genomics.

Genomic Variation and Gene Expression

Explores whole genome association studies, eQTL mapping, and genomic variation's impact on gene expression.

Quantile Normalization in Genomics

Explores quantile normalization in genomics, emphasizing data preparation, loading, filtering, and the significance of accurate gene expression analysis.

Genetics: Project R #2

Explores the analysis of genotypes and variants data through a Genome-Wide Association Study, focusing on the association between genetic variants and phenotypes like height.

Sex differences in immunity: Part I

Delves into sex differences in immunity, covering biological mechanisms, genomics, and clinical consequences.

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