Explores the complexity and fundamental capabilities of cancer, focusing on hallmarks like sustained proliferative signaling and evading growth suppressors.
Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.
Explores replicative immortality in cancer cells, focusing on telomere erosion, telomerase activity, and the role of p53 in maintaining genomic stability.
Explores how inflammation promotes tumor growth and immunosuppression, focusing on the role of inflammatory cells like MDSCs and neutrophils in the tumor microenvironment.
Covers the decline of cancer death rates, conventional and targeted anticancer drugs, surgical oncology, radiotherapy, chemotherapy, resistance mechanisms, and the history of targeted drugs and EGFR targeting.
