Course

CH-422: Catalyst design for synthesis

Lectures in this course (15)

Explores the history of catalysis, Nobel Prizes in the field, types of catalysis, and modern challenges.

Introduces the basics of homogeneous catalysis, focusing on reaction mechanisms and catalyst design.

Covers organometallic reactions, carbene complexes, metathesis, and polymerization.

Delves into olefin coordination mechanisms, phosphine dissociation, ligand effects, and catalyst reactivity.

Explores catalyst reactivity in metathesis reactions, emphasizing initiation rates and ligand effects.

Explores alkene metathesis mechanisms, total synthesis strategies, and hydrogenation selectivities.

Delves into the detailed reaction mechanism of hydrogenation, emphasizing Wilkinson's catalyst and the impact of ligand design.

Explores the mechanisms of homogeneous hydrogenation, catalyst properties, asymmetric hydrogenation, and chiral ligands.

Explores hydrogenation catalysts, catalyst loadings, selectivities, BINAP-Ru complexes, and asymmetric hydrogenation of alcohols.

Explores the history and significance of the Kumada Coupling reaction in transition metal catalysis.

Explores Ru-catalyzed water oxidation, catalyst comparison, and metal oxide performance in the oxygen evolution reaction.

Covers versatile methods for C-C bond formation using different organometallic reagents and organic halides.

Explores the mechanisms and ligand effects in cross-coupling reactions.

Explores C-N coupling with biarylphosphine ligands, covering mechanisms, applications, and challenges in C-O coupling reactions with Pd complexes.

Covers catalyst design for synthesis, focusing on activity trends and mechanisms.