Lectures related to Insulin Receptor Activation: Signaling Mechanisms

Protein Phosphorylation: Mechanisms and Regulation

Explores protein phosphorylation, its structural effects, kinase activity, and its role in signaling and disease.

Protein Phosphorylation: Mechanisms & Regulation

Explores protein phosphorylation, detailing common modifications like acetylation and ubiquitination, kinase specificity, and activation mechanisms.

Receptor Tyrosine Kinases: Signalling and Regulation

Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.

Posttranslational Modifications: Phosphorylation and Protein Phosphatases

Covers posttranslational modifications, focusing on phosphorylation and protein phosphatases, and explains kinase specificity assays and the optimal phosphorylation consensus.

Regulation Mechanisms Overview

Covers phosphorylation, ubiquitinylation, methylation, and more in biological regulation.

Cell Signalling: Receptors and Pathways

Explores cell signalling mechanisms, including receptors, pathways, and signal transduction for gene regulation and cellular responses.

Tyrosine Kinases & Ras Signaling

Explores tyrosine kinases, Ras activation, lipid signaling, cancer implications, and signal transduction in cells.

Nuclear Receptors: Signalling and Health Implications

Explores nuclear receptors, JAK-STAT pathway, growth factors, endocrine disruptors, and estrogen receptors.

Post-translational Modifications of Proteins

Provides an overview of protein post-translational modifications, including phosphorylation, ubiquitination, and acylation.

Cellular Communication: Signaling Pathways and Receptors

Delves into the importance of intercellular communication and the diverse signaling pathways involved in cellular responses.

Bacterial Signalling: Two-component Systems

Explores bacterial two-component signalling systems, gene regulation, chemotaxis, and flagellar rotation in E. coli.

Cell Membrane Receptors: General Principles

Explains cell membrane receptors, signal transduction, and second messengers.

Metabolism: Catabolism and Regulation

Explores catabolic pathways, energy production, and metabolic regulation in cells.

Metabolism and Hormones

Explores metabolic processes in different tissues and the role of hormones.

Analyzing Post-Translational Modifications: Techniques and Challenges

Covers the analysis of post-translational modifications using mass spectrometry, focusing on techniques, challenges, and the significance of phosphoproteomics.

Altered Pathways in Cancer: Signaling Cascades and Mutations

Explores cancer pathways, major signaling cascades, and mutations in RAS and BRAF genes.

Metabolic Signaling: Glycolysis and ATP Production

Explores glycolysis, ATP production, and metabolic signaling in cancer and drug discovery.

Electron Transport Chain: Proton Pumps and Coenzyme Q

Explores the Electron Transport Chain in mitochondria, focusing on proton pumps and Coenzyme Q.

Cell Patterning and Signalling Pathways

Explores cell patterning, signalling pathways, and genetic mutations in biological development.

DNA Damage Checkpoint

Explores the DNA damage checkpoint, cell cycle regulation, repair mechanisms, and key proteins involved.