Explores Alzheimer's disease, anxiety, pain, and the renin-angiotensin system, including the development of the first renin inhibitor for clinical treatment.
Explores kinase inhibitors, their types, mechanisms, and experimental evaluation, emphasizing the significance of covalent drugs in modern pharmaceutical research.
Explores enzyme activity modulation and small-molecule drug mechanisms, focusing on reversible and irreversible inhibition, progress curves, and covalent bond formation.
Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.
Delves into identifying drug targets, ensuring efficacy, and maintaining safety in medical chemistry, covering genetic tests, chirality, stereochemistry, drug resistance, and drug-likeness rules.
Explores Micro-ElectroMechanical Systems (MEMS) development, ion channels, patch clamp technique, drug discovery, and PDMS integration in microfluidic systems.