Explores programmed cell death mechanisms, including apoptosis and autophagy, with a focus on their implications in various organisms and regeneration processes.
Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.
Explores the definition, frequency, classification, and types of cancer, including carcinomas, sarcomas, hematopoietic malignancies, and neuroectodermal tumors.
Delves into synthetic biology, assembling molecular components for biological functions in living cells, including gene expression control and engineered receptor signaling.
Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.
Explores the complexity and fundamental capabilities of cancer, focusing on hallmarks like sustained proliferative signaling and evading growth suppressors.