Explores DNA repair mechanisms, focusing on BER and NER, cellular responses to DNA damage, and genetic disorders impacting DNA repair and cancer susceptibility.
Explores the maternal-to-zygotic transition in early embryonic development, focusing on key processes like zygotic genome activation and cell cycle regulation.
Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.
Covers DNA damage types, repair mechanisms, UV-induced damage, survival curves, NER deficiency consequences, tumor suppressor genes, and cancer prevention.
Explores cellular senescence mechanisms induced by mitogenic signals, DNA damage, and oncogenes, emphasizing the role of key regulatory proteins and the impact on cell division.