Lectures related to Biomolecular Condensation: Hsf1 in Stress Response

Early Events in the Heat Shock Response: Action in the Nucleus

Explores early events in the Heat Shock Response, focusing on Hsf1 regulation, Hsp70 dynamics, and the role of Sis1.

Heat Shock Transcription Factors: Regulation and Targets

Explores Heat Shock Transcription Factors' regulation and targets in response to stress, including HSF2's dynamic expression and impact on cell adhesion.

Prokaryotic Transcription: Operons and Sigma Factors

Explores prokaryotic transcription, operons, sigma factors, gene regulation, and DNA loops in bacteria.

Protein Disaggregation by Hsp70 Chaperone System

Explores protein disaggregation by the Hsp70 chaperone system and the significance of aggregate modification for protein refolding.

DNA Structure and Gene Expression

Explores DNA structure, gene expression, RNA transcription, and protein manufacturing in cells, including the crucial role of RNA polymerase.

DNA Structure and Transcription

Explores DNA structure, replication, transcription, mRNA translation, and gene expression regulation.

Hsp70 Interaction with Measles Virus Nucleoprotein

Explores the interaction between hsp70 and the intrinsically disordered Ntail domain of the measles virus nucleoprotein.

Molecular Mechanism of Hsp70 Chaperones: Interactions with Cochaperones and Substrates

Explores the molecular mechanism of Hsp70 chaperones, focusing on interactions with cochaperones and substrates.

RNA Functions: Transcription and Translation

Explores RNA functions in transcription, translation, and gene regulation, including defense mechanisms and viral infections.

Cellular Heat Shock Response: Rethinking the Significance

Delves into the cellular heat shock response, emphasizing the absence of a sensor mechanism and the restoration of misfolded protein aggregates.

Protein Synthesis: Recombinant Expression

Explores protein synthesis, genetic code, transcription, translation, and recombinant protein expression using vectors and plasmids.

Chaperone Mechanism of Grp94: Elucidating ER Protein Quality Control

Explores the chaperone mechanism of Grp94 in ER protein quality control and client protein activation.

Protein-Repair Machineries: Evolution and Function

Explores the evolution and function of protein-repair machineries, emphasizing the role of ATP-fueled unfolding machines in preventing protein aggregation and promoting proper folding.

Chaperone-Mediated Disaggregation: Amyloid Fibrils and Hsp70

Explores chaperone-mediated disaggregation of amyloid fibrils by Hsp70 in neurodegenerative diseases.

RNA Switches: Design and Applications

Explores RNA switches design and applications, focusing on exploiting nature's design principles to build new biomolecular components and networks.

Mitochondrial Hsp70: Import and Protein Folding

Explores the role of mitochondrial Hsp70 in protein import and folding processes, stress response pathways, and experimental techniques.

Genetic Circuits: Synthetic Biology

Explores genetic circuits design in synthetic biology, from regulatory mechanisms to plasmid construction.

Gene Transcription: Central Dogma and Transcription Process

Covers the process of gene transcription, RNA processing, and translation from DNA to mRNA.

Hsp70 Mechanism: Unfolding & Entropic Pulling

Explores Hsp70's role in protein unfolding and entropic pulling, discussing chaperone-driven stabilization and ATP hydrolysis.

Eukaryotic Transcription: Initiation and Elongation

Explores eukaryotic transcription initiation, elongation, and gene regulation complexity.