Explores Chemical Biology's interdisciplinary nature, enzyme inhibition, genetic methods, and metabolic regulation, highlighting its real-world relevance through recent Nobel Prize contributions.
Discusses the inclusion of fermented foods in global food guides, exploring their benefits and risks, enzyme kinetics, and the history of food enzymes.
Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.
Explores enzyme activity modulation and small-molecule drug mechanisms, focusing on reversible and irreversible inhibition, progress curves, and covalent bond formation.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.
Explores enzyme inhibition mechanisms, including competitive, uncompetitive, and mixed inhibition, as well as autocatalysis and their impact on enzyme kinetics.