Delves into pioneer transcription factors, chromatin organization, and cell fate transitions, showcasing examples of reprogramming and discussing the potential applications in regenerative medicine.
Explores transcription factors in reprogramming somatic cells to induced pluripotent stem cells and the correlation between Hox gene expression and morphological boundaries.
Explores the applications of embryonic stem cells in biomedical research, disease modeling, and potential therapeutic interventions, including the types of stem cells and the challenges they face.
Explores early embryogenesis, ES cell differentiation, disease modeling, neuronal function, genome editing, 'minibrains', in vitro retina and intestine, single-cell analysis, and lineage tracing.
Explores organoids, miniature tissue constructs mimicking living tissues, covering derivation methods, applications, and bridging in vitro and in vivo models.
Covers the formation and applications of organoids, including brain, skin, and intestinal organoids, as well as the engineering of tissues and the concept of organ-on-a-chip.
