Explores nuclear receptors' core signaling and the impact of endocrine disruptors on the endocrine system, including the inhibitory effects of compounds like eugenol on the estrogen receptor.
Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.
Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.
Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.
Explores gene regulation through transcription mechanisms and chromatin accessibility, emphasizing the importance of transcription factors and gene regulatory networks.
Explores gene regulation mechanisms, including chromatin accessibility, DNA looping, and transcription factors' role in controlling cellular functions.
Explores Heat Shock Transcription Factors' regulation and targets in response to stress, including HSF2's dynamic expression and impact on cell adhesion.
