Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.
Explores the definition, frequency, classification, and types of cancer, including carcinomas, sarcomas, hematopoietic malignancies, and neuroectodermal tumors.
Explores nuclear receptors' core signaling and the impact of endocrine disruptors on the endocrine system, including the inhibitory effects of compounds like eugenol on the estrogen receptor.
Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.
Explores drug targets like ligand-gated ion channels and kinase-linked receptors, discussing mechanisms of action, clinical uses, and insulin's physiological context.
Explores metabolic signaling through glycolysis, the Warburg effect, and glycolytic switches in cancer, emphasizing ATP as the universal energy carrier.
Explores the complexity of cancer, challenges in research translation, and the applications of tissue engineering for cancer models and drug screening.
