Explores synchrotrons, X-ray techniques, crystallography, enzyme structures, mutant engineering, and the future of macromolecular crystallography.
Explores protein structure determination using NMR and Cryo-EM techniques, covering chemical shifts, isotope labeling, NOE, and high-resolution imaging methods.
Explores enzyme catalytic strategies, including proteases and carbonic anhydrase, inhibition mechanisms, and specificity of serine proteases.
Covers the fundamentals of inhibitor design and analysis, emphasizing the importance of targeting cysteine residues.
