Protein Reactivity and Chemical Probes

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Related lectures (32)

Chemistry of Saturated Carbon Compounds: Reactions and Mechanisms

Provides an overview of saturated carbon compounds and their chemical reactions, focusing on halogenoalkanes and substitution mechanisms.

Enzymology: Structure, Kinetics, and Inhibition

Covers enzyme structure, kinetics, inhibition, specificity, and practical applications in enzymology.

Kinetics: Time as a Variable

Explores the role of time in chemical reactions, the importance of catalysts, and the measurement of binding kinetics.

Introduction into Catalysis: Basics and Mechanisms

Introduces the basics of catalysis, including types of catalysis, energy profiles, and the importance of catalysts in speeding up reactions.

Chemical Biology meets Drug Discovery

Explores Chemical Biology, Drug Discovery, enzyme kinetics, and inhibition methods, including competitive and non-competitive inhibition.

Platinum Drugs for Cancer: Mechanisms and Variants

Covers platinum-based cancer drugs, electrophilic aromatic substitution, cross-coupling reactions, and SN2 and SN1 mechanisms.

Synchrotrons and X-ray Techniques

Explores synchrotrons, X-ray techniques, crystallography, enzyme structures, mutant engineering, and the future of macromolecular crystallography.

Reaction Kinetics: Temperature Influence

Discusses temperature's impact on reaction rates, activation energy, collision efficiency, reaction mechanisms, catalysis, and enzymatic catalysis.

Cellular Communication and Metabolism: Energy Transformation Principles

Discusses cellular communication, metabolism, energy transformation, and the role of enzymes in biochemical reactions.

Covalent Inhibitors Kinetics

Explores the kinetics of covalent inhibitors, focusing on compounds A and B.

Kinase Inhibitors: Types and Mechanisms

Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.

Quantitative Proteomics: SILAC for SM-Protein Interactions

Explores SILAC for SM-protein interactions, enzyme inhibitors, and proteome-level signaling analysis.

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