Explores the mechanisms of ALS, focusing on SOD1 pathology, including toxic gain of function, protein misfolding, ER stress, and mitochondrial dysfunction.
Explores the importance of protein-ligand interactions, focusing on binding affinities and energetic landscapes, with implications for drug development and specificity.
Explores the EXSCALATE4COV project, focusing on computational drug discovery for COVID-19 treatments and the collaboration between academia and industry.
Explores proteostasis regulation through chaperone interactions and post-translational modifications, revealing insights into protein quality control mechanisms.