Telomeres and CancerExplores telomeres' role in cancer biology, covering telomerase, replication problems, ALT pathway, and Nobel Prize-winning discoveries.
Replicative ImmortalityExplores replicative immortality in cancer cells, focusing on telomere erosion, telomerase activity, and the role of p53 in maintaining genomic stability.
DNA Damage CheckpointExplores the DNA damage checkpoint, cell cycle regulation, repair mechanisms, and key proteins involved.
DNA Structure and FunctionExplores DNA structure, histone interactions, polymerase function, nucleosome organization, chromatin compaction, cell cycle phases, FISH analysis, and telomere structure.
Telomeres and CancerExplores telomeres' crucial role in cancer biology, covering telomerase, replication problems, ALT pathway, and TERRA functions.
Cancer Biology: p53 and DNA RepairExplores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.
Cell Cycle RegulationExplores cell cycle regulation, focusing on G1/S transition control mechanisms and the impact of Myc on cell proliferation.
Tumor Suppressor p53Explores the tumor suppressor gene p53, its functions, regulation, and implications for cancer.
Maternal-to-zygotic TransitionExplores the Maternal-to-zygotic Transition in early embryos, discussing key factors and processes influencing development.
DNA Replication: EukaryotesExplores DNA replication in eukaryotic cells, emphasizing pre-replicative complexes and replication regulation mechanisms.