Explores metabolic diversity, oxidative phosphorylation, and Fe/Mn cycles in biological systems, emphasizing electron transfer mechanisms and environmental implications.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.
Explores the design and validation of targeted protein degraders, including PROTACs and molecular glue compounds, emphasizing the importance of proper analyses and validations in TPD research.