Lectures related to Transcellular Chaperone Signalling: Activating Organismal Proteostasis in C. elegans

Protein-Repair Machineries: Evolution and Function

Explores the evolution and function of protein-repair machineries, emphasizing the role of ATP-fueled unfolding machines in preventing protein aggregation and promoting proper folding.

Digestive System: Introduction and General Structure

Covers the introduction and detailed anatomy of the digestive system, highlighting its purpose in managing nutrients and the challenges it faces.

Chaperone-Mediated Disaggregation: Amyloid Fibrils and Hsp70

Explores chaperone-mediated disaggregation of amyloid fibrils by Hsp70 in neurodegenerative diseases.

Hierarchical Organization in Human Body

Explores the hierarchical organization in the human body, from molecules to organs, and the significance of water.

Molecular Chaperone Action: Small Heat Shock Proteins

Explores the molecular chaperone action of small heat shock proteins in proteostasis, focusing on their interaction with misfolded proteins and amyloid fibrils.

Protein Disaggregation by Hsp70 Chaperone System

Explores protein disaggregation by the Hsp70 chaperone system and the significance of aggregate modification for protein refolding.

Epididymis: Histological Structure and Function

Explores the histological structure and function of the epididymis, emphasizing cell types and secretion processes.

Mitochondrial Proteotoxic Stress Response

Explores the sub-mitochondrial proteotoxic stress response using yeast as a model organism.

Biliary Vesicle Morphology

Explores the structure and function of the biliary vesicle as a bile reservoir.

Mitochondrial Hsp70: Import and Protein Folding

Explores the role of mitochondrial Hsp70 in protein import and folding processes, stress response pathways, and experimental techniques.

Chaperone Mechanism of Grp94: Elucidating ER Protein Quality Control

Explores the chaperone mechanism of Grp94 in ER protein quality control and client protein activation.

Cellular Heat Shock Response: Rethinking the Significance

Delves into the cellular heat shock response, emphasizing the absence of a sensor mechanism and the restoration of misfolded protein aggregates.

Muscle Biomechanics

Explores muscle anatomy, function, force generation, and measurement techniques in biomechanics.

Bradykinin: Humoral Vasomotricity

Explores the discovery and significance of bradykinin in arterial vasomotricity and vasodilation.

Energy Transformations: ATP and Cellular Work

Explores major themes in biology, focusing on energy transformations within cellular systems and the crucial role of adenosine triphosphate (ATP).

Muscle Biomechanics: Functional Anatomy and Force Generation

Explores muscle functional anatomy, force generation, and biomechanical incorporation of spring and active elements.

Digestive Physiology: Motility and Histology

Explores digestive motility, contraction patterns, and histological features of the digestive tract, including the role of pacemakers and defecation mechanisms.

Early Events in the Heat Shock Response: Action in the Nucleus

Explores early events in the Heat Shock Response, focusing on Hsf1 regulation, Hsp70 dynamics, and the role of Sis1.

Male Reproductive System Anatomy

Explains the male reproductive system anatomy, including vas deferens, prostate, and seminal vesicles.

Negative Feedback: Body Temperature Regulation

Explores negative feedback in body temperature regulation and how it maintains core temperature around 37°C.