Covers the basics of polymer biophysics, including DNA conformation modeling and the Boltzmann principle, emphasizing the exponential decay of correlations between segments.
Covers the historical development of genomics, from Sanger sequencing to high-throughput technologies and cost reductions, highlighting the impact of key players like Craig Venter.
Explores single molecule sequencing strategies, including sequencing by synthesis and real-time sequencing based on zero mode waveguides, as well as DNA translocation through nanopores.
