Analyzes a mutant DDX3 enzyme's ATPase activity and inhibitor development, covering RNA chaperones, crystal structures, and mass spectrometry-based protein profiling.
Covers the design and analysis of inhibitors for next-generation covalent drugs, focusing on target engagement and the importance of cysteine targeting.
Explores metabolic signaling through glycolysis, the Warburg effect, and glycolytic switches in cancer, emphasizing ATP as the universal energy carrier.
