Lectures related to Drug Target Discovery: Thermal Shift Profiling

Identifying Drug Targets with Thermal-Shift Profiling

Showcases correlations between different organs' thermal profiles to identify drug targets.

Quantitative Proteome Profiling: Chemical Target Identification

Explores quantitative proteome profiling for drug target identification through activity-based protein profiling and advanced mass spectrometry techniques.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, hit identification methods, and its application in target-based drug discovery.

Protein Therapeutics: Blood Proteins and Enzymes

Explores blood composition, proteins, coagulation, diseases treated with enzymes, and case studies on genetic disorders.

Proteomics: Post-Translational Modifications and Interactions

Explores proteomics for post-translational modifications and protein interactions.

Proteomics Profiling Methods

Explores proteomics profiling methods, including ABPP, MS approaches, and quantitative target identification using SILAC and TMT labeling.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, exploring hit identification, lead optimization, and screening methods.

Activity-based Protein Profiling: Druggable Sites Identification

Explores Activity-based Protein Profiling for druggable site identification and strategies to minimize off-target reactivity of covalent inhibitors.

Protein Mass Spectrometry and Proteomics: Techniques and Applications

Explores protein mass spectrometry techniques, including labeling methods, quantitation, and biomarker discovery.

Protein Mass Spectrometry and Proteomics

Covers protein mass spectrometry, proteomics techniques, challenges, and applications in analyzing complex protein mixtures.

Protein-Protein Interaction Networks

Explores protein-protein interaction networks, binding importance, experimental approaches, drug target identification, and network construction.

Interrogating SAR in Medical Chemistry

Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.

Protein Mass Spectrometry and Proteomics

Explores protein mass spectrometry, chromatographic techniques, and quantitative proteomic workflows, including SILAC and isobaric tagging methods.

Frontiers in Chemical Biology

Explores the druggable proteome, PROTACS strategy, ubiquitin attachment, and drug development paradigms.

Protein Profiling: Mass Spectrometry and Target-ID Tools

Explores protein profiling using mass spectrometry, target enrichment techniques, and quantitative proteomics.

Protein Mass Spectrometry and Proteomics

Explores protein mass spectrometry, proteomic strategies, separations techniques, and protein identification methods using MS/MS data.

Protein Structure Exploration

Explores protein composition, synthesis, purification, and analysis techniques for understanding protein structure and function.

Interrogating SAR: Medicinal Chemistry

Covers medicinal chemistry basics, high-throughput screening, lead discovery milestones, and compound selectivity in drug optimization.

Explores SERF-related proteins' functions in amyloid acceleration and G-quadruplex binding, shedding light on their complex mechanisms.

Exploring Proteins: Structure, Purification, and Analysis

Covers protein exploration, purification, and analysis methods, including sequencing, concentration measurement, and antibody detection.