Explores protein aggregation in neurodegenerative diseases, emphasizing the need to rethink treatment strategies and understand the role of post-translational modifications.
Explores translation, mutations, ribosome function, protein folding, and degradation processes, emphasizing the genetic code's role in protein synthesis.
Explores proteinopathy mapping, connecting proteotoxicity to intrinsic functions of aggregation-prone proteins, with a focus on alpha-synuclein and Parkinson's Disease.
Explores spatial regulation of ribosomal protein translation and the role of the ER in protein synthesis, covering advanced concepts and experimental designs.
Explores the evolution and function of protein-repair machineries, emphasizing the role of ATP-fueled unfolding machines in preventing protein aggregation and promoting proper folding.
Explores proximity-specific ribosome profiling and translational dynamics with high resolution, covering spatial regulation, cell architecture, ER's role, and advanced techniques.
Explores proximity-specific ribosome profiling and translational dynamics with high resolution, covering translation in different cells and the ER's role in protein synthesis.