Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.
Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.
Explores Heat Shock Transcription Factors' regulation and targets in response to stress, including HSF2's dynamic expression and impact on cell adhesion.
Explores receptors, ligands, and their role in signal transduction, including the activation of the immune system and the significance of multivalency in receptor-ligand interactions.
Explores the basics and structures of G protein-coupled receptors, covering signaling schemes, structures, historical background, drug targeting, and recent advancements.
