Lectures related to General Topics of Pharmacology: Mechanisms and Toxicity

Selective Drug Targeting Mechanisms

Explores selective drug targeting mechanisms, resistance development, tuberculosis incidence, BCR-ABL mutations, tyrosine kinase inhibitors, drug toxicity, interactions, and toxicology studies.

Anticancer Therapies I: De Palma

Covers the decline of cancer death rates, conventional and targeted anticancer drugs, surgical oncology, radiotherapy, chemotherapy, resistance mechanisms, and the history of targeted drugs and EGFR targeting.

Understanding Cancer Therapies

Explores cancer therapies, including chemotherapies and targeted therapies, discussing mechanisms of action, limitations, and the development of resistance.

Platinum Drugs for Cancer: Mechanism and Variants

Delves into the mechanism of platinum-based drugs for cancer treatment and the development of improved versions.

Identifying Drug Targets: Safety and Efficacy

Delves into identifying drug targets, ensuring efficacy, and maintaining safety in medical chemistry, covering genetic tests, chirality, stereochemistry, drug resistance, and drug-likeness rules.

Identifying Correct Target in Medical Chemistry

Explores target identification, efficacy, and safety in medical chemistry, emphasizing the importance of on-target specificity and drug design.

Small Molecule Drugs: Cardiovascular Diseases

Explores the molecular basis and treatment of cardiovascular diseases, focusing on atherosclerosis, hypertension, and drug therapies.

Pharmacology: Autonomic Nervous System and Drug Effects

Explores the pharmacology of the autonomic nervous system and drug effects.

Enzyme Drug Targets

Explores enzyme drug targets, tyrosine kinase inhibitors, vascular tone control, and viral life cycle interventions.

Drug Targets: Adrenergic Signaling

Explores drug targets and adrenergic signaling, covering receptors, enzymes, and transporter proteins.

Drug Delivery: Artificial Viruses

Explores using artificial viruses for targeted drug delivery in cancer treatment, aiming to minimize side effects.

Pharmacology: Drug Targets and Mechanisms

Discusses ligand-receptor binding, drug targets, insulin physiology, NSAIDs, and tyrosine kinase inhibitors.

Adrenal Gland: Development and Stress Response

Explores the anatomy, development, and stress response of the adrenal gland, detailing its role in the body's reaction to stress.

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Pharmacological Targets and Interventions

Explores targets for drug action and the design of specific inhibitors.

Introduction: small molecule drugs for cancer

Introduces small molecule drugs for cancer treatment, covering drug discovery, mechanisms of action, and historical development of anti-cancer agents.

SEGREGATION of KINETIC REACTIVITY & BINDING AFFINITY

The paper focuses on the importance of reversible interactions to potency and mechanisms of drug resistance.

Immune Cell Engineering: Targeting Checkpoint Inhibitors

Explores immune cell engineering for cancer therapy, emphasizing checkpoint inhibitor targeting through innovative delivery methods.

Drug Targets: ligand-gated ion channels and kinase-linked receptors

Explores drug targets in ligand-gated ion channels and kinase-linked receptors, focusing on GABAA receptors, benzodiazepines, and insulin therapy.

Drug Targets: Ligand-Gated Ion Channels and Kinase-Linked Receptors

Explores drug targets like ligand-gated ion channels and kinase-linked receptors, discussing mechanisms of action, clinical uses, and insulin's physiological context.