Publications by Vincent Jacquemet

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Vincent Jacquemet, Jean-Marc Vesin, Adrian Luca

Introduction: Electrical heterogeneity in the atria has been consistently linked with the initiation and perpetuation of atrial fibrillation (AF). The present model-based study investigated the contribution of action potential duration (APD) heterogeneitie ...

Oxford Univ Press2016

Influence of atrial substrate on local capture induced by rapid pacing of atrial fibrillation

Vincent Jacquemet, Jean-Marc Vesin, Alexandru Rusu

Preliminary studies showed that the septum area was the only location allowing local capture of both the atria during rapid pacing of atrial fibrillation (AF) from a single site. The present model-based study investigated the influence of atrial substrate ...

Oxford University Press2014

Estimating the time scale and anatomical location of atrial fibrillation spontaneous termination in a biophysical model

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

Due to their transient nature, spontaneous terminations of atrial fibrillation (AF) are difficult to investigate. Apparently, confounding experimental findings about the time scale of this phenomenon have been reported, with values ranging from 1 s to 1 mi ...

Springer-Verlag2012

Optimizing Local Capture of Atrial Fibrillation by Rapid Pacing: Study of the Influence of Tissue Dynamics

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

While successful termination by pacing of organized atrial tachycardias has been observed in patients, rapid pacing of AF can induce a local capture of the atrial tissue but in general no termination. The purpose of this study was to perform a systematic e ...

Springer Verlag2010

Adaptive Multiple Frequency Tracking Algorithm: Detection of Stable Atrial Fibrillation Sources from Standard 12-Lead ECG

Vincent Jacquemet, Jean-Marc Vesin, Mathieu Lemay, Cédric Duchene

The detection of stable atrial fibrillation (AF) sources remains one of the major challenges in the AF management. In this study, we investigated the feasibility of detecting stable AF sources from (non invasive) data simulated by means of numerical proced ...

2009

The Role of Atrial Modeling in the Development of ECG Processing Tools

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger, Mathieu Lemay, Laurent Renaud Uldry, Cédric Duchene

The standard ECG remains the most common non-invasive tool for assessing atrial fibrillation. Specific signal processing techniques have been developed to improve the diagnosis. However, validation of such tools is challenging and comprehensive invasive da ...

2009

The effect of tissue geometry on the activation recovery interval of atrial myocytes

Vincent Jacquemet

The propagation of electric activity inside a realistically-shaped, thick-walled model of the atria was studied. The membrane kinetics was based on the formulations of Courtemanche, Ramirez and Nattel. In spite of the assumed uniformity of all kinetics par ...

2009

Spontaneous termination of atrial fibrillation: study of the effect of atrial geometry in a biophysical model

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

We studied the mechanisms of spontaneous termination of atrial fibrillation in a biophysical model of human atria, during the eight seconds preceding termination. The earliest detectable changes in the cycle length and the number of wavefronts occurred abo ...

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Dominant Rotors in Atrial Fibrillation identified by means of Spectral Analysis

Vincent Jacquemet

Blackwell Publishing2009

Activity Level of an Atrial Ectopic Focus Observed Through the Equivalent Dipole: a Biophysical Model

Vincent Jacquemet, Jean-Marc Vesin, Mathieu Lemay, Cédric Duchene

Quantifying the role of atrial ectopic foci in the initiation and the maintenance of atrial fibrillation (AF) is a relevant clinical problem. This study aims at assessing the relation between the activity level of an ectopic focus and the complexity of the ...

2009

Ensuring stability in models of atrial kinetics

Vincent Jacquemet

The membrane kinetics of human atrial myocytes as formulated by Courtemance, Ramierz and Nattel has been studied while focusing on its progression toward stationary solutions during long term repetitive stimulation. An algorithm is presented for finding th ...

2009

Spectral analysis of the ECG identifies dominant rotors during atrial fibrillation

Vincent Jacquemet, Lukas Kappenberger, Mathieu Lemay

2008

Phase-Rectified Signal Averaging Used to Estimate the Dominant Frequencies in ECG Signals During Atrial Fibrillation

Vincent Jacquemet, Jean-Marc Vesin, Yann Prudat, Mathieu Lemay

2008

Adaptation of the standard 12-lead electrocardiogram system dedicated to the analysis of atrial fibrillation

Vincent Jacquemet, Zenichi Ihara

Objective: The objective of the study was to design a lead system aimed at studying atrial fibrillation (AF), while being anchored to the standard 12-lead system. Methods: The location of 4 of the 6 precordial electrodes was optimized while leaving the rem ...

2007

Cancellation of Ventricular Activity in the ECG: Evaluation of novel and existing methods

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger, Mathieu Lemay

2007

Steady-state Solutions in Mathematical Models of Atrial Cell Electrophysiology and their Stability

Vincent Jacquemet

The steady states of the Fenton–Karma, the Courtemanche and the Nygren cell models were studied by determining the fixed points of the dynamical system describing their cell kinetics. The linear stability of the fixed points was investigated, as well as th ...

2007

Phase-Rectified Signal Averaging. A useful Tool for the Estimation of the Dominant Frequency in ECG Signals during Atrial Fibrillation

Vincent Jacquemet, Jean-Marc Vesin, Yann Prudat, Mathieu Lemay

2007

Pacemaker Activity Resulting from the Coupling with Nonexcitable Cells

Vincent Jacquemet

2006

Analysis of electrocardiograms during atrial fibrillation

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger

The research discussed in this article is motivated by the search for an optimal classification of the different types of atrial fibrillation (AF) on the basis of recorded atrial signals. This would facilitate the selection of an optimal therapy. This arti ...

2006

Finite Volume Stiffness Matrix for Solving Anisotropic Cardiac Propagation in 2D and 3D Unstructured Meshes

Vincent Jacquemet

2005