Publications by Horst Pick | EPFL Graph Search

Print-Light-Synthesis of ruthenium oxide thin film electrodes for electrochemical sensing applications

Print-Light-Synthesis (PLS) combines the inkjet printing of a ruthenium precursor ink with the simultaneous photo-induced generation of ruthenium oxide films. During PLS, inkjet-printing generates on conductive as well as insulating substrates micrometer-t ...

Elsevier BV2025

Purification of Cellulose and Chitin Polymers and Other Value-Added Products from the Microalga Chlorella vulgaris Using a Green Biorefinery Process

Horst Pick, Christian Ludwig, Enio Daniel Zanchetta, Eya Nicodeme

Microalgae produce renewable biomass at high efficiency by using photosynthesis to capture the greenhouse gas CO2 from the atmosphere and releasing O2. Chlorella vulgaris is one of the most frequently cultivated unicellular green microalgae of commercial r ...

2025

Abiotic stress approaches for enhancing cellulose and chitin production in Chlorella vulgaris

Horst Pick, Christian Ludwig, Enio Daniel Zanchetta, Eya Nicodeme

Several lines of evidence point to the presence of both, cellulose and chitin as structural constituents of the Chlorella vulgaris cell wall. These biopolymers are favourable building blocks for many sustainable industrial applications for instance as bioc ...

Elsevier BV2025

Print-Light-Synthesis of Gold Thin Film Electrodes for Electrochemical Sensing

Horst Pick, Andreas Stephan Lesch, Emanuela Maiorano

The one-step fabrication of gold films by inkjet printing of a gold precursor ink and its photochemical reduction by exposure to UV light is presented. Inkjet printing creates on a substrate with high control micrometer-thin reaction volumes in which upon ...

Wiley2023

Effective removal of the rotifer Brachionus calyciflorus from a Chlorella vulgaris microalgal culture by homogeneous solar photo-Fenton at neutral pH

Horst Pick, Christian Ludwig, Adrian Pulgarin, Stefanos Giannakis, Jérémie Decker, Dominik Refardt, Jiahua Chen

In this study, a citrate-modified photo-Fenton process was successfully applied to decontaminate a Chlorella vulgaris microalgae culture spiked with the rotifer Brachionus calyciflorus (5 individuals mL−1). The applied treatment (1 mg L−1 Fe2+, 20 mg L−1 H ...

2022

RB714, RB715, RB716, RB717 and RB718 antibodies recognize the histone HMtA protein from Methanobrevibacter smithii by ELISA

Horst Pick, Duncan-Bruce Sutherland

The recombinant antibodies RB714, RB715, RB716, RB717 and RB718 detect by ELISA the M. smithi histone HMtA protein fused to a GST. ...

2022

Rapid Noninvasive Skin Monitoring by Surface Mass Recording and Data Learning

Hubert Girault, Horst Pick, Natalia Gasilova, Andreas Stephan Lesch, Tzu-En Lin, Yingdi Zhu, Milica Jovic

Skin problems are often overlooked due to a lack of robust and patient-friendly monitoring tools. Herein, we report a rapid, noninvasive, and high-throughput analytical chemical methodology, aiming at real-time monitoring of skin conditions and early detec ...

2021

Soft-probe-scanning electrochemical microscopy reveals electrochemical surface reactivity of E. coli biofilms

Hubert Girault, Horst Pick, Emad Oveisi, Andreas Stephan Lesch, Sorour Darvishi

Investigating and understanding dynamic biofilm growth mechanisms is challenging, often because state-of-the-art optical characterization tools provide limited information. Micrometric electrochemical imaging of Escherichia coli biofilms using Soft-Probe-S ...

2021

Algal cellulose, production and potential use in plastics: Challenges and opportunities

Horst Pick, Christian Ludwig, Adrian Pulgarin, Enio Daniel Zanchetta, Eya Nicodeme, Tobias Borgmeyer

The development of new biodegradable plastic materials from renewable sources is a major challenge for plastic industries to provide sustainable alternatives to petroleum plastic. Bio-based plastics are generally obtained from photosynthetic biomass such a ...

2021

Highly Loaded Mildly Edge‐Oxidized Graphene Nanosheet Dispersions for Large‐Scale Inkjet Printing of Electrochemical Sensors

Hubert Girault, Horst Pick, Andreas Stephan Lesch, Victor Costa Bassetto, Yingdi Zhu, Milica Jovic, Bhawna Nagar

Inkjet printing of electrochemical sensors using a highly loaded mildly edge‐oxidized graphene nanosheet (EOGN) ink is presented. An ink with 30 mg/mL EOGNs is formulated in a mixture of N‐methyl pyrrolidone and propylene glycol with only 30 min of sonicat ...

2020

The G protein coupled receptor CXCR4 designed by the QTY code becomes more hydrophilic and retains cell signaling activity

Horst Vogel, Horst Pick

G protein-coupled receptors (GPCRs) are vital for diverse biological functions, including vision, smell, and aging. They are involved in a wide range of diseases, and are among the most important targets of medicinal drugs. Tools that facilitate GPCR studi ...

NATURE RESEARCH2020

Skin cell analysis

Hubert Girault, Horst Pick, Andreas Stephan Lesch, Tzu-En Lin, Yingdi Zhu, Milica Jovic

The present invention describes an adhesive tape stripping transfer method for quick and non-invasive diagnosis of skin diseases by MALDI-TOF mass spectrometry analysis. Cells from the epidermis layer of a suspicious skin area of a patient are collected us ...

2020

Computational modeling of the olfactory receptor Olfr73 suggests a molecular basis for low potency of olfactory receptor-activating compounds

Horst Vogel, Horst Pick, Thamani Dahoun, Shuguang Yuan, Marc Brugarolas Campillos

The mammalian olfactory system uses hundreds of specialized G-protein-coupled olfactory receptors (ORs) to discriminate a nearly unlimited number of odorants. Cognate agonists of most ORs have not yet been identified and potential non-olfactory processes m ...

Springer2019

MALDI Detection of Exosomes: A Potential Tool for Cancer Studies

Hubert Girault, Horst Pick, Natalia Gasilova, Tzu-En Lin, Yingdi Zhu

Matrix-assisted laser desorption ionization time-of-flight mass spectrometry is used to detect intact whole exosomes, yielding exosomal fingerprints within minutes. This rapid exosome detection approach is proposed as a potential tool for cancer studies. M ...

2019

Tape-Stripping Electrochemical Detection of Melanoma

Hubert Girault, Horst Pick, Andreas Stephan Lesch, Tzu-En Lin, Yingdi Zhu, Sorour Darvishi

A noninvasive electrochemical melanoma detection approach based on using adhesive tapes for collecting and fixing cells from a suspicious skin area and transferring the cells into a scanning electrochemical microscope (SECM) is presented. The adhesive laye ...

AMER CHEMICAL SOC2019

Detection of bacteria

Hubert Girault, Horst Pick, Andreas Stephan Lesch, Yingdi Zhu, Milica Jovic

A method for bacteria detection and the assessment of the antimicrobial susceptibility profile uses a bacterial viability assay based on combining a highly efficient affinity bacteria enrichment/ separation with an electrochemical redox interrogation measu ...

2019

Single-Vesicle Assays Using Liposomes and Cell-Derived Vesicles: From Modeling Complex Membrane Processes to Synthetic Biology and Biomedical Applications

Horst Vogel, Horst Pick, Ana Catarina Rodrigues Alves

The plasma membrane is of central importance for defining the closed volume of cells in contradistinction to the extracellular environment. The plasma membrane not only serves as a boundary, but it also mediates the exchange of physical and chemical inform ...

AMER CHEMICAL SOC2018

Engineered Multivalent Sensors to Detect Coexisting Histone Modifications in Living Stem Cells

Horst Pick, Cédric Deluz, Bart Deplancke, Aurore Marie-France Delachat, Nora Guidotti, Beat Fierz, David Michael Suter, Antonio Carlos Alves Meireles Filho, Carolin Christine Lechner, Andreas Linus Bachmann

2018

Detection of antimicrobial resistance-associated proteins by titanium dioxide-facilitated intact bacteria mass spectrometry

Hubert Girault, Horst Pick, Liang Qiao, Natalia Gasilova, Yingdi Zhu, Milica Jovic

Titanium dioxide-modified target plates were developed to enhance intact bacteria analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. The plates were designed to photocatalytically destroy the bacterial envelope struct ...

2018

Maldi device and methods of preparation and use thereof

Hubert Girault, Horst Pick, Liang Qiao, Yingdi Zhu, Milica Jovic

A target plate for enhanced matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) analysis of intact biological entities. The target plate comprises an electrically conductive substrate (1) covered at least partially with immobilised pho ...

2018