Publications by Fabrice Merenda

Crossed fiber optic Bessel beams for curvilinear optofluidic transport of dielectric particles

René Salathé, Fabrice Merenda, Kyunghwan Oh

Due to its unique non-diffracting and self-reconstructing nature, Bessel beams have been successfully adopted to trap multiple particles along the beam's axial direction. However, prior bulk-optic based Bessel beams have a fundamental form-factor limitatio ...

Optical Soc Amer2013

Microfluidic array cytometer based on refractive optical tweezers for parallel trapping, imaging and sorting of individual cells

René Salathé, Horst Vogel, Fabrice Merenda, Joachim Piguet, Michael Werner

Analysis of genetic and functional variability in populations of living cells requires experimental techniques capable of monitoring cellular processes such as cell signaling of many single cells in parallel while offering the possibility to sort interesti ...

Royal Society of Chemistry2011

High-resolution microscopy and photolithography devices using focusing micromirrors

René Salathé, Fabrice Merenda, Bastien Rachet

The invention relates to large-field high-resolution microscopy and photolithography setups operating with polychromatic light. It includes the use of a plurality of focusing micromirrors. ...

2010

Validation of a one-dimensional model of the systemic arterial tree

Nikolaos Stergiopoulos, Fabrice Merenda, Philippe Reymond

A distributed model of the human arterial tree including all main systemic arteries coupled to a heart model is developed. The one-dimensional (1-D) form of the momentum and continuity equations is solved numerically to obtain pressures and flows throughou ...

2009

Miniaturized optical tweezers based on high-na micro-mirrors

René Salathé, Johann Rohner, Fabrice Merenda

The invention relates to an optical tweezer device including at least one light source (2) and one three-dimensional optical trap (9,10), said optical trap comprising one focusing micro-mirror (7) which is adapted to reflect and focus at least a portion of ...

2009

Validation Of I D Model Of The Systemic Arterial Tree Including The Cerebral Circulation

Nikolaos Stergiopoulos, Fabrice Merenda, Philippe Reymond, Daniel Ruefenacht

American Soc Mechanical Engineers, Three Park Avenue, New York, Ny 10016-5990 Usa2009

Three-dimensional force measurements in optical tweezers formed with high-NA micromirrors

László Forró, René Salathé, Fabrice Merenda, Mathieu Grossenbacher, Sylvia Jeney

The three-dimensional trap stiffness of optical tweezers formed with high-NA micromirrors is investigated by back-focal-plane interferometry and power spectrum analysis. Normalized stiffness values of kappa(xy)/P-trap =1.2(mu N/m)/mW and kappa(z)/P-trap = ...

Optical Society of America2009

Micro-optics for multiple laser trapping in microfluidics

Fabrice Merenda

Optical trapping allows manipulating very small objects – varying from Angstöms to micron size particles – without physical contact by taking advantage of laser light. This technique, relying on light momentum transfer, allows manipulating biological matte ...

EPFL2008

Comparison between various types of multiple optical tweezers

René Salathé, Johann Rohner, Fabrice Merenda, Jean-Marc Fournier

Many types of optical tweezers arrays have been proposed and developed for use in conjunction with microfluidics for bio-chemical essays. Trap arrays rely on different methods allowing various degrees of flexibility and relative trapping efficiencies. Amon ...

Spie-Int Soc Optical Engineering2008

Micro-optics for optical trapping in microfluidics - art. no. 66440P

René Salathé, Johann Rohner, Fabrice Merenda, Jean-Marc Fournier, Elodie Lamothe

Micro-optical compo nents offer several possibilities for creating large matrices of optical traps, either when working on inverted microscopes, or by directly integrating miniaturized optical components at the level of a micro-fluidic chip. In thisarticle ...

2007

Refractive multiple optical tweezers for parallel biochemical analysis in micro-fluidics

René Salathé, Horst Vogel, Johann Rohner, Fabrice Merenda, Jean-Marc Fournier

We present a multiple laser tweezers system based on refractive optics. The system produces an array of 100 optical traps thanks to a refractive microlens array, whose focal plane is imaged into the focal plane of a high-NA microscope objective. This refra ...

2007

Combining multiple optical trapping with microflow manipulation for the rapid bioanalytics on microparticles in a chip

Guy Delacrétaz, René Salathé, Philippe Renaud, Johann Rohner, Fabrice Merenda, Gerben Boer

An array of four independent laser traps is combined with a polydimethylsiloxane microfluidic chip to form a very compact system allowing parallel processing of biological objects. Strong three dimensional trapping allows holding objects such as functional ...

American Institute of Physics2007

Miniaturized optical tweezer array with an array of reflective elements for reflecting the light back to a focal area

Guy Delacrétaz, René Salathé, Fabrice Merenda, Gerben Boer

Apparatus for forming a single or a plurality of threedimensional optical traps, the apparatus comprising: a. A collimated light source that is directed onto an array of focalizing refractive or diffractive elements providing a single or a plurality of foc ...

2007

Multiple optical trapping in high gradient interference fringes

René Salathé, Johann Rohner, Fabrice Merenda, Jean-Marc Fournier

In biological investigations, many protocols using optical trapping call for the possibility to trap a large number of particles simultaneously. Interference fringes provide a solution for massively parallel micro-manipulation of mesoscopic objects. Concur ...

2006

Escape trajectories of single-beam optically trapped micro-particles in a transverse fluid flow

Guy Delacrétaz, René Salathé, Johann Rohner, Fabrice Merenda, Gerben Boer

Optical Society of America2006