Publications by Philippe Reymond

Near-wall hemodynamic parameters quantification in in vitro intracranial aneurysms with 7 T PC-MRI

ObjectiveWall shear stress (WSS) and its derived spatiotemporal parameters have proven to play a major role on intracranial aneurysms (IAs) growth and rupture. This study aims to demonstrate how ultra-high field (UHF) 7 T phase contrast magnetic resonance ...

SPRINGER2023

Transient Neurovascular Interface for Minimally Invasive Neural Recording and Stimulation

Philippe Reymond, Diego Ghezzi, Laura Ferlauto, Adele Fanelli, Elodie Geneviève Zollinger

Neural interfaces are used to mitigate the burden of traumatic injuries, neurodegenerative diseases, and mental disorders. However, the transient or permanent placement of an interface in close contact with the neural tissue requires invasive surgery, pote ...

Wiley2021

Experimental evaluation of direct thromboaspiration efficacy according to the angle of interaction between the aspiration catheter and the clot

Mohamed Bouri, Philippe Reymond

Background Successful direct thromboaspiration (DTA) is related to several factors such as clot consistency, size, and location. It has also been demonstrated recently that the angle of interaction (AOI) formed by the aspiration catheter and the clot is re ...

2021

How Flow Reduction Influences the Intracranial Aneurysm Occlusion: A Prospective 4D Phase-Contrast MRI Study

Mohamed Farhat, Philippe Reymond, Pierre Bouillot

BACKGROUND AND PURPOSE: Flow-diverter stents are widely used for the treatment of wide-neck intracranial aneurysms. Various parameters may influence intracranial aneurysm thrombosis, including the flow reduction induced by flow-diverter stent implantation, ...

American Society of Neuroradiology (ASNR)2019

A 1D model of the arterial circulation in mice

Nikolaos Stergiopoulos, Philippe Reymond, Patrick Segers, Bram Trachet, Lydia Aslanidou

At a time of growing concern over the ethics of animal experimentation, mouse models are still an indispensable source of insight into the cardiovascular system and its most frequent pathologies. Nevertheless, reference data on the murine cardiovascular an ...

2016

Arterial stiffness of the internal carotid artery does not distinguish patients with stable unruptured aneurysms from normal controls

Nikolaos Stergiopoulos, Philippe Reymond, Daniel Ruefenacht, Edouard Fonck

Karger2013

Arterial stiffness of the internal carotid artery does not distinguish patients with stable unruptured aneurysms from normal controls

Nikolaos Stergiopoulos, Philippe Reymond, Daniel Ruefenacht, Edouard Fonck

Karger2013

Physiological simulation of blood flow in the aorta: comparison of hemodynamic indices as predicted by 3-D FSI, 3-D rigid wall and 1-D models

Nikolaos Stergiopoulos, Alfio Quarteroni, Simone Deparis, Philippe Reymond, Paolo Crosetto

Interest in patient-specific blood-flow circulation modeling has increased substantially in recent years. The availability of clinical data for geometric and elastic properties together with efficient numerical methods has now made model rendering feasible ...

Elsevier2013

Ambulatory arterial stiffness index does not accurately assess arterial stiffness

Nikolaos Stergiopoulos, Philippe Reymond, Patrick Segers

Introduction: The ambulatory arterial stiffness index (AASI), derived from ambulatory blood pressure monitoring (ABPM) recordings, has been proposed as a surrogate marker of arterial stiffness. However, there is controversy to what extent it reflects stiff ...

Lippincott, Williams & Wilkins2012

Response to comments regarding Vardoulis O, et al., Impact of Aortic Grafts on Arterial Pressure: A Computational Fluid Dynamics Study. Eur J Vasc Endovasc Surg 2011;42:704-10

Nikolaos Stergiopoulos, Philippe Reymond, Bryn Andrew Martin, Orestis Vardoulis, Eline Coppens

Elsevier2012

Flow diversion treatment: intra-aneurismal blood flow velocity and WSS reduction are parameters to predict aneurysm thrombosis

Luca Augsburger, Philippe Reymond, Daniel Ruefenacht

To evaluate the haemodynamic changes induced by flow diversion treatment in cerebral aneurysms, resulting in thrombosis or persisting aneurysm patency over time. Eight patients with aneurysms at the para-ophthalmic segment of the internal carotid artery we ...

Springer Verlag2012

3D simulation of the aqueous flow in the human eye

Nikolaos Stergiopoulos, Philippe Reymond, Sylvain Roy, Adan Villamarin, Reda Hasballa, Orestis Vardoulis

Glaucoma results in an increase in the resistance of the aqueous humor outflow, which in turn leads to an increase of the intraocular pressure (IOP). Several treatments are proposed to reduce and stabilize the IOP that include medications, filtering surger ...

Elsevier Sci Ltd2012

Generic and patient-specific models of the arterial tree

Nikolaos Stergiopoulos, Philippe Reymond, Orestis Vardoulis

Recent advance in imaging modalities used frequently in clinical routine can provide description of the geometrical and hemodynamical properties of the arterial tree in great detail. The combination of such information with models of blood flow of the arte ...

Springer Netherlands2012

A coupled hydrodynamic model of the cardiovascular and cerebrospinal fluid system

Nikolaos Stergiopoulos, Philippe Reymond, Bryn Andrew Martin

Martin BA, Reymond P, Novy J, Baledent O, Stergiopulos N. A coupled hydrodynamic model of the cardiovascular and cerebrospinal fluid system. Am J Physiol Heart Circ Physiol 302: H1492-H1509, 2012. First published January 20, 2012; doi: 10.1152/ajpheart.006 ...

2012

Patient-specific mean pressure drop in the systemic arterial tree, a comparison between 1-D and 3-D models

Nikolaos Stergiopoulos, Philippe Reymond, François Lazeyras

One-dimensional models of the systemic arterial tree are useful tools for studying wave propagation phenomena, however, their formulation for frictional losses is approximate and often based on solutions for developed flow in straight non-tapered arterial ...

Elsevier2012

Systolic Hypertension Mechanisms: Effect of Global and Local Proximal Aorta Stiffening on Pulse Pressure

Nikolaos Stergiopoulos, Nico Westerhof, Philippe Reymond

Decrease in arterial compliance leads to an increased pulse pressure, as explained by the Windkessel effect. Pressure waveform is the sum of a forward running and a backward running or reflected pressure wave. When the arterial system stiffens, as a result ...

Springer US2012

Intracranial Stents Being Modeled as a Porous Medium: Flow Simulation in Stented Cerebral Aneurysms

Nikolaos Stergiopoulos, Luca Augsburger, Philippe Reymond

Intracranial aneurysms may be treated by flow diverters, alternatively to stents and coils combination. Numerical simulation allows the assessment of the complex nature of aneurismal flow. Endovascular devices present a rather dense and fine strut network, ...

Springer US2011

Computational Hemodynamics in Cerebral Aneurysms: The Effects of Modeled Versus Measured Boundary Conditions

Philippe Reymond

Modeling of flow in intracranial aneurysms (IAs) requires flow information at the model boundaries. In absence of patient-specific measurements, typical or modeled boundary conditions (BCs) are often used. This study investigates the effects of modeled ver ...

2011

Impact of Aortic Grafts on Arterial Pressure: A Computational Fluid Dynamics Study

Nikolaos Stergiopoulos, Philippe Reymond, Bryn Andrew Martin, Orestis Vardoulis, Eline Coppens

Objective: Vascular prostheses currently used in vascular surgery do not have the same mechanical properties as human arteries. This computational study analyses the mechanisms by which grafts, placed in the ascending aorta (proximal) and descending aorta ...

Elsevier2011

Validation of the Arteriograph working principle: questions still remain

Nikolaos Stergiopoulos, Philippe Reymond, Patrick Segers, Bram Trachet

Lippincott, Williams & Wilkins2011