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Simone Cavadini

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Related publications (11)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Structural mechanism of cGAS inhibition by the nucleosome

Rudolf Hovius, Simone Cavadini, Beat Fierz, Andrea Ablasser, Sélène-Véronique Glück, Baptiste Claude André Guey, Alexiane Clara Decout, Kristina Makasheva, Pauline Ambre Melenec

The DNA sensor cGAS initiates innate immune responses following microbial infection, cellular stress, and cancer1. Upon activation by double-stranded DNA, cytosolic cGAS produces 2’3’ cyclic GMP-AMP and triggers inflammatory cytokine and type I interferon ...

2020

Micelles for delivery of nitric oxide

Nikolaos Stergiopoulos, Jeffrey Alan Hubbell, Simone Cavadini, Yun Suk Jo, Jay Gantz, Tyler Nerton Thacher, Davide Demurtas

We designed block copolymer pro-amphiphiles and amphiphiles for providing very long-term release of nitric oxide (NO). A block copolymer of N-acryloylmorpholine (AM, as a hydrophile) and N-acryloyl-2,5-dimethylpiperazine (AZd, as a hydrophilic precursor) w ...

2009

Indirect detection of nitrogen-14 in solid-state NMR spectroscopy

Simone Cavadini

This thesis describes new methods for the detection of 14N nuclei by solid-state nuclear magnetic resonance. So far, the low natural abundance (0.4 %) 15N isotope has been widely used to study nitrogen-containing samples because of its spin-1/2 nature. The ...

EPFL2009