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Richard Alan Mimna

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Related publications (8)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Switch-peptides as folding precursors in self-assembling peptides and amyloid fibrillogenesis

Karine Murat, Jérémy Bérard, Richard Alan Mimna, Marie-Stéphanie Camus, Hilal Lashuel, Adrian Schmid

The study of conformational transitions of peptides has obtained considerable attention recently because of their importance as a mol. key event in a variety of degenerative diseases. However, the study of peptide self-assembly into beta-sheets and amyloid ...

2007

Toward the design of highly efficient, readily accessible peptide N-caps for the induction of helical conformations

Richard Alan Mimna

A series of novel peptide N-caps was designed with an emphasis on ease of synthesis and an abundance of hydrogen bond acceptors. Different scaffolds based on sugars, cyclic hydrocarbons, and amino acids are developed with a variety of hydrogen bond accepto ...

Kluwer Academic Publishers, Springer2007

Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept

Richard Alan Mimna, Marie-Stéphanie Camus, Hilal Lashuel, Adrian Schmid

Reversal of amyloid formation through a controlled induced transformation from beta-sheet to sol. alpha-helix structures through the use of a switch element S could have an important consequences understanding the mechanisms of amyloid formation and cleara ...

Wiley-VCH Verlag GmbH2007