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Thomas Lemmin

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Related publications (15)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Effect of the Synaptic Plasma Membrane on the Stability of the Amyloid Precursor Protein Homodimer

Thomas Lemmin, Matteo Dal Peraro, Alessandro Barducci, Martina Audagnotto

The proteolytic cleavage of the transmembrane (TM) domain of the amyloid precursor protein (APP) releases amyloid-beta (A beta) peptides, which accumulation in the brain tissue is an early indicator of Alzheimer's disease. We used multiscale molecular dyna ...

Amer Chemical Soc2016

Lipid Builder: A Framework To Build Realistic Models for Biological Membranes

Thomas Lemmin, Matteo Dal Peraro, Christophe Bovigny, Nicolas Grégoire Maïno, Giorgio Elikem Tamo

The physical and chemical characterization of biological membranes is of fundamental importance for understanding the functional role of lipid bilayers in shaping cells and organelles, steering vesicle trafficking and promoting membrane-protein signaling. ...

Amer Chemical Soc2015

A coiled coil switch mediates cold sensing by the thermosensory protein DesK

Thomas Lemmin, Matteo Dal Peraro, Luciano Andres Abriata

The thermosensor histidine kinase DesK from Bacillus subtilis senses changes in membrane fluidity initiating an adaptive response. Structural changes in DesK have been implicated in transmembrane signaling, but direct evidence is still lacking. On the basi ...

Wiley-Blackwell2015