Orbitally shaken bioreactors are an emerging alternative to stirred-tank bioreactors for large-scale mammalian cell culture, but their fluid dynamics is still not well defined. Among the theoretical and practical issues that remain to be resolved, the char ...
This work focuses on the finite element discretization of boundary value problems whose solution features either a discontinuity or a discontinuous conormal derivative across an interface inside the computational domain. The interface is characterized via ...
Mammalian cell cultures have become a major topic of research in the biopharmaceutical industry. This kind of cells requires specific conditions to grow. In this thesis, we study the hydrodynamics of orbitally shaken reactors (OSR), a recently introduced k ...
