Publications by Giuseppe Foffi

Simulation and Theory of Antibody Binding to Crowded Antigen-Covered Surfaces

Paolo De Los Rios, Francesco Piazza, Giuseppe Foffi

In this paper we introduce a fully flexible coarse-grained model of immunoglobulin G (IgG) antibodies parametrized directly on cryo-EM data and simulate the binding dynamics of many IgGs to antigens adsorbed on a surface at increasing densities. Moreover, ...

Public Library Science2016

Memory effects in schematic models of glasses subjected to oscillatory deformation

Giuseppe Foffi, Davide Fiocco

We consider two schematic models of glasses subjected to oscillatory shear deformation, motivated by the observations, in computer simulations of a model glass, of a nonequilibrium transition from a localized to a diffusive regime as the shear amplitude is ...

Iop Publishing Ltd2015

Hard sphere-like glass transition in eye lens alpha-crystallin solutions

Nicolas Dorsaz, Giuseppe Foffi

We study the equilibrium liquid structure and dynamics of dilute and concentrated bovine eye lens alpha-crystallin solutions, using small-angle X-ray scattering, static and dynamic light scattering, viscometry, molecular dynamics simulations, and mode-coup ...

National Academy of Sciences2014

Macromolecular crowding: chemistry and physics meet biology (Ascona, Switzerland, 10-14 June 2012) PREFACE

Francesco Piazza, Giuseppe Foffi

Iop Publishing Ltd2013

Partial slip at fluid-solid boundaries by multiparticle collision dynamics simulations

Giuseppe Foffi, Samuel Hanot, Maxim Belushkin

The understanding of the exact boundary conditions at the interface between a solid and a fluid is becoming increasingly important, as the limitations of the no-slip boundary condition are becoming apparent, especially in micro- and nanofluidics applicatio ...

Royal Soc Chemistry2013

Arrested demixing opens route to bigels

Nicolas Dorsaz, Giuseppe Foffi, Francesco Varrato, Maxim Belushkin

Understanding and, ultimately, controlling the properties of amorphous materials is one of the key goals of material science. Among the different amorphous structures, a very important role is played by colloidal gels. It has been only recently understood ...

National Academy of Sciences2012

Role of fluid-density correlations in hydrodynamics: a multiparticle collision dynamics simulation study

Giuseppe Foffi, Maxim Belushkin

Hydrodynamic interactions play a pivotal role in the dynamical behaviour of mesoscale systems such as colloidal suspensions, yet isolating their contribution from other effects remains a key challenge. Hydrodynamic correlations within a fluid are a consequ ...

Royal Soc Chemistry2012

Backtracking of Colloids: A Multiparticle Collision Dynamics Simulation Study

Giuseppe Foffi, Maxim Belushkin

The role of sound in the dynamics of mesoscale systems is typically neglected, since frequently the associated time scales are much smaller than all the other time scales of interest. However, for sufficiently small objects embedded in a solvent with a suf ...

2011

Phase separation in binary eye lens protein mixtures

Nicolas Dorsaz, Giuseppe Foffi

Liquid–liquid phase separation occurs in young mammalian eye lenses and in concentrated solutions of isolated eye lens proteins, and has been linked to some forms of cataract. Here we study theoretically the protein compositions and cloud temperatures of t ...

2011

Apollonian Packings as Physical Fractals (vol 109, pg 2663, 2011)

Giuseppe Foffi, Francesco Varrato

Taylor & Francis2011

Apollonian packings as physical fractals

Giuseppe Foffi, Francesco Varrato

The Apollonian packings (APs) of spheres are fractals that result from a space-filling procedure. We discuss the finite size effects for finite intervals s is an element of [s(min), s(max)] between the largest and the smallest sizes of the filling spheres. ...

Taylor & Francis2011

Resonances arising from hydrodynamic memory in Brownian motion

László Forró, Sylvia Jeney, Giuseppe Foffi, Flavio Maurizio Mor, Maxim Belushkin, Matthias Grimm

Observation of the Brownian motion of a small probe interacting with its environment provides one of the main strategies for characterizing soft matter. Essentially, two counteracting forces govern the motion of the Brownian particle. First, the particle i ...

2011

Apollonian packings as physical fractals

Giuseppe Foffi, Francesco Varrato

The Apollonian packings (APs) of spheres are fractals that result from a space-filling procedure. We discuss the finite size effects for finite intervals s is an element of [s(min), s(max)] between the largest and the smallest sizes of the filling spheres. ...

Taylor & Francis2011

Effective Forces in Square Well and Square Shoulder Fluids

Giuseppe Foffi, Davide Fiocco

We derive an analytical expression for the effective force between a pair of macrospheres immersed in a sea of microspheres, in the case where the interaction between the two unlike species is assumed to be a square well or a square shoulder of given range ...

American Chemical Society2010

Inertial effects in diffusion-limited reactions

Nicolas Dorsaz, Francesco Piazza, Giuseppe Foffi

Diffusion-limited reactions are commonly found in biochemical processes such as enzyme catalysis, colloid and protein aggregation and binding between different macromolecules in cells. Usually, such reactions are modeled within the Smoluchowski framework b ...

Institute of Physics2010

Phase behaviour of the symmetric binary mixture from Thermodynamic Perturbation Theory

Nicolas Dorsaz, Giuseppe Foffi

We study the phase behaviour of symmetric binary mixtures of hard core Yukawa (HCY) particles via thermodynamic perturbation theory (TPT). We show that all the topologies of phase diagram reported for the symmetric binary mixtures are correctly reproduced ...

2010

Spinodal surface of a free energy model for eye lens protein mixtures: Relevance for cataracts

Nicolas Dorsaz, Giuseppe Foffi

We studied the phase behavior of a model binary mixture of eye lens crystallin proteins using first-order thermodynamic perturbation theory. The instability boundary, or spinodal surface, was found to be very sensitive to the strength of the attraction bet ...

Amer Inst Physics, 2 Huntington Quadrangle, Ste 1No1 D, Melville, Ny 11747-4501 Usa2009

Colloidal characterization and thermodynamic stability of binary eye lens protein mixtures

Nicolas Dorsaz, Giuseppe Foffi

We present a study of binary mixtures of eye lens crystallin proteins. A coarse-grained model of aqueous aand γ-crystallin mixtures based on molecular dynamics simulations and SANS experiments is proposed. Thermodynamic perturbation theory is implemented t ...

2009

A method for the enumeration of the floppy modes and the calculation of the associated entropy

Giuseppe Foffi

We present a method that is based on the Ladd-Frenkel (LF) thermodynamic integration for the study of the rigidity of networks of particles bonded together by short-ranged square well attractive potentials. We show that, by taking the limit of the attracti ...

2008

Short range attractive colloids: Dynamics and energy landscape properties

Giuseppe Foffi

We discuss the static and dynamical properties of a model of short range attractive colloidal systems. Our model is a binary mixture of particles interacting with a modified Lennard-Jones potential that we simulated by molecular dynamics. As previously fou ...

2008