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Igor Allaman

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Related publications (33)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Lactate in the brain: from metabolic end-product to signalling molecule

Pierre Magistretti, Igor Allaman

Lactate in the brain has long been associated with ischaemia; however, more recent evidence shows that it can be found there under physiological conditions. In the brain, lactate is formed predominantly in astrocytes from glucose or glycogen in response to ...

2018

Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection

Pierre Marquet, Pierre Magistretti, Pascal Jourdain, Igor Allaman, Kaspar Rothenfusser

L-Lactate is a positive modulator of NMDAR-mediated signaling resulting in plasticity gene induction and memory consolidation. However, L-Lactate is also able to protect neurons against excito-toxic NMDAR activity, an indication of a mitigating action of L ...

Nature Research2018

Functional consequences of brain glycogen deficiency on the sleep-wake cycle regulation in PTG-KO mice

Pierre Magistretti, Igor Allaman, Gabriele Grenningloh, Sophie Burlet Godinot

WILEY2018