Publications by Thomas Berger | EPFL Graph Search

Neuronal circuitry is often considered a clean slate that can be dynamically and arbitrarily molded by experience. However, when we investigated synaptic connectivity in groups of pyramidal neurons in the neocortex, we found that both connectivity and syna ...

2011

Effective Stimuli for Constructing Reliable Neuron Models

Henry Markram, Thomas Berger, Felix Schürmann, Sean Lewis Hill, Idan Segev

The rich dynamical nature of neurons poses major conceptual and technical challenges for unraveling their nonlinear membrane properties. Traditionally, various current waveforms have been injected at the soma to probe neuron dynamics, but the rationale for ...

2011

Organizing neural networks

Henry Markram, Rodrigo de Campos Perin, Thomas Berger

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for organizing trained and untrained neural networks. In one aspect, a neural network device includes a collection of node assemblies interconnected by betwe ...

2011

Brief Bursts Self-Inhibit and Correlate the Pyramidal Network

Henry Markram, Gilad Silberberg, Rodrigo de Campos Perin, Thomas Berger

Inhibitory pathways are an essential component in the function of the neocortical microcircuitry. Despite the relatively small fraction of inhibitory neurons in the neocortex, these neurons are strongly activated due to their high connectivity rate and the ...

Public Library of Science2010

Properties of neocortical microcircuits

Thomas Berger

The mammalian neocortex is one of the most complex brain areas, integrating all sensory modalities and allowing the animal to perform high level cognitive operations. Despite some cytoarchitectural specializations, the general neocortical structure is rema ...

EPFL2009

Frequency-dependent disynaptic inhibition in the pyramidal network: a ubiquitous pathway in the developing rat neocortex

Henry Markram, Gilad Silberberg, Rodrigo de Campos Perin, Thomas Berger

The general structure of the mammalian neocortex is remarkably similar across different cortical areas. Despite certain cytoarchitectural specializations and deviations from the general blueprint, the principal organization of the neocortex is relatively u ...

2009

Inferring connection proximity in networks of electrically coupled cells by subthreshold frequency response analysis

Henry Markram, Michele Pignatelli, Thomas Berger, Michele Giugliano, Corrado Cali

Electrical synapses continuously transfer signals bi-directionally from one cell to another, directly or indirectly via intermediate cells. Electrical synapses are common in many brain structures such as the inferior olive, the subcoeruleus nucleus and the ...

Springer US2008

The quantitative single-neuron modeling competition

Wulfram Gerstner, Renaud Jolivet, Thomas Berger, Felix Schürmann, Richard Naud

As large-scale, detailed network modeling projects are flourishing in the field of computational neuroscience, it is more and more important to design single neuron models that not only capture qualitative features of real neurons but are quantitatively ac ...

Springer Verlag2008

Quantitative single-neuron modeling: competition 2008

Wulfram Gerstner, Laurent Badel, Thomas Berger, Richard Naud

How well are single-cell properties reproduced by the present-day neuronal models? Recently, several labs have approached this question by assessing the quality of the models with respect to spike timing prediction or characteristic features of the voltage ...

2008