Johanna Generosi

This person is no longer with EPFL

About
Privacy
Disclaimer

Graph Chatbot

Related publications (5)

Biological samples studied by optical nanospectroscopy

Johanna Generosi

The different parts of the electromagnetic spectrum result in diverse effects upon interaction with matter: according to the wavelength, the radiation has energy appropriate for the excitation of a specific physical process. X-rays can be used as a tool to ...

EPFL2009

AMPA receptor imaging by infrared scanning near-field optical microscopy

Giorgio Margaritondo, Kai Johnsson, Harald Hirling, Michel Kropf, Johanna Generosi

Infrared scanning near-field optical microscopy is used to detect AMPA-type glutamate receptor clusters in hippocampal neuron cells. AMPA's GluR2-subunits were marked with the fluorophore Alexa488 and high-resolution micrographs were taken at 6.25 µm wavel ...

Wiley2008

Photobleaching-free infrared near-field microscopy localizes molecules in neurons

Giorgio Margaritondo, Kai Johnsson, Harald Hirling, Michel Kropf, Johanna Generosi

High-resolution detection of specific molecules in cells is a major challenge in biology. We show that infrared scanning near-field microscopy can detect the spatial distribution of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid–type glutamate r ...

2008

Infrared scanning near-field optical microscopy investigates order and clusters in model membranes

Giorgio Margaritondo, Johanna Generosi

Due to its surface sensitivity and high spatial resolution, scanning near-field optical microscopy (SNOM) has a significant potential to study the lateral organization of membrane domains and clusters. Compared to other techniques, infrared near-field micr ...

2008

Spectroscopic infrared near-field microscopy and x-ray reflectivity studies of order and clustering in lipid membranes

Giorgio Margaritondo, Johanna Generosi

Lipid membranes were studied by infrared scanning near-field optical microscopy at several wavelengths and by x-ray reflectivity. Together with the x-ray data, the optical images indicate the formation of locally ordered multiple bilayers, and the topograp ...

AIP American Institute of Physics2006

Page 1 of 1