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Le Xiao

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

BMP signaling specifies the development of a large and fast CNS synapse

Graham Knott, Ralf Schneggenburger, Le Xiao, Elin Kristina Kronander, Enida Gjoni

excitatory synapses with multiple active zones ensure reliable and fast information transfer at specific points in neuronal circuits. However, the mechanisms that determine synapse size in CNS circuits are largely unknown. Here we use the calyx of Held syn ...

Nature Publishing Group2013

Identification of Signaling Mechanisms Determining the Development of Large Excitatory Synapses in the Lower Auditory System

In the brainstem auditory circuit of mammals and birds, excitatory synapses with extraordinarily large size have evolved, which ensure fast membrane potential signaling mediated by large, multiquantal excitatory postsynaptic currents (EPSCs). The so-called ...

EPFL2011

Developmental expression of Synaptotagmin isoforms in single calyx of Held-generating neurons

Heike Runne, Ralf Schneggenburger, Le Xiao, Yunyun Han, Olexiy Kochubey, Heather Mary Elizabeth Murray

The large glutamatergic calyx of Held synapse in the auditory brainstem has become a powerful model for studying transmitter release mechanisms, but the molecular bases of presynaptic function at this synapse are not well known. Here, we have used single-c ...

2010